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Week 2: Ebola Virus Notes.

by: Becca LeBoeuf

Week 2: Ebola Virus Notes. Biology 233

Becca LeBoeuf

GPA 3.0

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About this Document

Here are the notes we covered in class on Friday. These notes consist of content on the Ebola virus.
Microbiology survey
Teri Shors
#Biology #Bio233 #MicrobialSurvey #Ebola
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This 3 page Bundle was uploaded by Becca LeBoeuf on Sunday February 14, 2016. The Bundle belongs to Biology 233 at University of Wisconsin - Oshkosh taught by Teri Shors in Summer 2015. Since its upload, it has received 32 views. For similar materials see Microbiology survey in Biology at University of Wisconsin - Oshkosh.


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Date Created: 02/14/16
Week 2 Notes:    ● Ebola Virus ­ 2014:  ○ Epicenter ­ Guinea & West Africa:  ■ Recognized by WHO in March 2014 as an Ebola epidemic.  ■ 3 Ebola intensive countries:  ● Guinea  ● Liberia  ● Sierra Leone  ○ Patient Zero ­ 2 year old, Meliandou village:  ■ Gueckedou: died on 12/6/13.  ■ Sister, mom, grandma, midwife, and nurse got infected and died.  ■ How did he get infected?  ● Natura; reservoir = bats, #1 source bushmeat because sources of  protein are scarce.  ● Hunters of bushmeat are most at risk by contact with blood and  bodily fluid.  ● Banning bushmeat changes traditions and removes a source of  protein.  ○ Bats: Natural Reservoir:  ■ Colony free­tailed bats. 50 meters from home of patient zero.  ■ Burned it down before testing.  ○ Ebola Virus Looks Like Spaghetti:  ■ Enveloped virus.  ■ Helical shaped.  ○ FINAL STATS:  ■ 28,602 cases (about 28,000).  ■ 11,301 deaths.  ■ Majority of cases between August and December 2014.  ■ Still some random cases now.  ○ Healthcare Workers Had 42.2% Time Higher Chance Of Infection:  ■ 40% of nurses.  ■ 25% of doctors.  ■ 4% of midwives.  ■ 5% lab techs.  ■ 11% other.  ○ Transmission:  ■ Contact with contaminated bodily fluids.  ● Bats (blood, feces, saliva).  ● Humans (bodily fluids).  ■ Healthcare workers at most risk.  ■ NOT AIRBORNE.    ○ Infectious Dose:  ■ Not known.  ■ Estimate 1­10 viruses.  ○ Dry Symptoms (early):  ■ Not contagious.  ■ Headache, fever, tired, etc.  ○ Wet Symptoms:  ■ Contagious.  ■ Diarrhea, vomit, rash, bleeding, etc.  ■ Usually will die.  ○ Ebola Virus Disease (official name):  ■ R­nought of 1 = always around (ex. cold store).  ● Above = epidemic (higher = respiratory).  ● Measles = R­nought of 18 (pertussis = 17).  ○ Incubation Period of Ebola:  ■ 8­21 days after infection.  ● Average: 8­10 days.  ○ Ebola Guinea = 2, spread to 2 more people:  ■ Ex: Ro=2.  ○ Why Was It So Bad?  ■ Diagnosed late.  ■ First time in West Africa.  ■ Quickly spread to populated cities (Conakry = capital of NG. 2 million  people, international airport).  ■ In small villages they can do contact tracing.  ■ Trace who patient was in contact with.  ○ Local Population Doesn’t Know What Ebola Is:  ■ Superstitious (thought western medicine was bringing it over to hurt  them).  ■ Fear and violence (within the whole world).  ■ No doctors, “traditional healers.”  ■ 72% of people polled were afraid.  ○ Cultural Practices:  ■ Unsafe burials.  ● Wash body.  ● Kiss face.  ● “Final bowl” used to wash hands.  ■ Ear bushmeat.  ○ Healthcare Infrastructure Fragile In West Africa:  ■ 1­2 doctors for every 100,000 people.  ■ Hospitals closed.  ■ Could not get supplies.  ■ Hidden cases, turned away.  ■ PPE (personal protective equipment) didn’t exist.  ○ No Antiviral Therapies.  ○ No Vaccines.         


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