New User Special Price Expires in

Let's log you in.

Sign in with Facebook


Don't have a StudySoup account? Create one here!


Create a StudySoup account

Be part of our community, it's free to join!

Sign up with Facebook


Create your account
By creating an account you agree to StudySoup's terms and conditions and privacy policy

Already have a StudySoup account? Login here

Polycystic kidney disease

by: Hanyao Foong

Polycystic kidney disease 1001

Hanyao Foong
Leonard M. Miller School of Medicine

Almost Ready


These notes were just uploaded, and will be ready to view shortly.

Purchase these notes here, or revisit this page.

Either way, we'll remind you when they're ready :)

Preview These Notes for FREE

Get a free preview of these Notes, just enter your email below.

Unlock Preview
Unlock Preview

Preview these materials now for free

Why put in your email? Get access to more of this material and other relevant free materials for your school

View Preview

About this Document

A comprehensive summary of two main polycystic kidney disease
Study Guide
50 ?




Popular in Medcine

Popular in Military Science

This 0 page Study Guide was uploaded by Hanyao Foong on Sunday January 3, 2016. The Study Guide belongs to 1001 at Leonard M. Miller School of Medicine taught by in Winter2015. Since its upload, it has received 37 views. For similar materials see Medcine in Military Science at Leonard M. Miller School of Medicine.

Similar to 1001 at Leonard M. Miller School of Medicine

Popular in Military Science


Reviews for Polycystic kidney disease


Report this Material


What is Karma?


Karma is the currency of StudySoup.

You can buy or earn more Karma at anytime and redeem it for class notes, study guides, flashcards, and more!

Date Created: 01/03/16
Autosomal dominant polycystic kidney disease ADPKD Common 11000 Innumerable cyst causing bilaterally enlarged kidneys ultimately destroying kidney parenchyma 85 mutation in PKD1 chromosome 16 D reach ESRF by age 505 15 mutation in PKD2 gene chromosome 4 reach ESRF by age 705 Symptoms Vague abdominalloin pain Haematuria Hypertension Urinary tract infection cysts infection Renal failure VVVVV Progressive increase in size often leads to abdominal discomfort and there may be haemorrhage into a cyst causing haematuria or infection Extrarenal benign hepatic cysts mitral valve prolapse berry aneurysm D subarachnoid haemorrhage SAH ovarian cysts diverticular disease Death from complications of CKD or Hypertension due to increased renin production Treatment gt Monitor UampE gt Hypertension should be treated aggressively ACE best choice target lt13080mm Hg gt Treat infections gt Dialysistransplantation for ESRF gt Genetic counselling can be clinically silent for many years so family screening is important gt Pain laparoscopic cyst removalnephrectomy gt Increased water intake decreased Na intake avoid caffeine may help Screening for PKD gt USS screening good sensitivity and speci city gt Genetic testing for PKD1 is dif cult as the gene is large and there are hundreds of described mutations gt Genetic testing for PKD2 mutations is available in specialist centres Screening for SAH gt using magnetic resonance angiography gt may be done in 1St degree relatives of those with SAHADPKD gt Some screen with no family hx esp for certain occupations eg Pilot gt Autosomal recessive polycystic kidney disease Rare 140 000 Mutation in Chromosome 6 Signs gt Many present in infancy with multiple renal cysts and Congenital hepatic brosis Signi cant oliguric renal failure in utero lead to Potter sequence Renal failure in utero lead to oligohydramnios D compression of developing fetus D limb deformities facial anomalies lowset ears and retrognathia and compression of chest D pulmonary hypoplasia cause of death


Buy Material

Are you sure you want to buy this material for

50 Karma

Buy Material

BOOM! Enjoy Your Free Notes!

We've added these Notes to your profile, click here to view them now.


You're already Subscribed!

Looks like you've already subscribed to StudySoup, you won't need to purchase another subscription to get this material. To access this material simply click 'View Full Document'

Why people love StudySoup

Jim McGreen Ohio University

"Knowing I can count on the Elite Notetaker in my class allows me to focus on what the professor is saying instead of just scribbling notes the whole time and falling behind."

Kyle Maynard Purdue

"When you're taking detailed notes and trying to help everyone else out in the class, it really helps you learn and understand the I made $280 on my first study guide!"

Bentley McCaw University of Florida

"I was shooting for a perfect 4.0 GPA this semester. Having StudySoup as a study aid was critical to helping me achieve my goal...and I nailed it!"

Parker Thompson 500 Startups

"It's a great way for students to improve their educational experience and it seemed like a product that everybody wants, so all the people participating are winning."

Become an Elite Notetaker and start selling your notes online!

Refund Policy


All subscriptions to StudySoup are paid in full at the time of subscribing. To change your credit card information or to cancel your subscription, go to "Edit Settings". All credit card information will be available there. If you should decide to cancel your subscription, it will continue to be valid until the next payment period, as all payments for the current period were made in advance. For special circumstances, please email


StudySoup has more than 1 million course-specific study resources to help students study smarter. If you’re having trouble finding what you’re looking for, our customer support team can help you find what you need! Feel free to contact them here:

Recurring Subscriptions: If you have canceled your recurring subscription on the day of renewal and have not downloaded any documents, you may request a refund by submitting an email to

Satisfaction Guarantee: If you’re not satisfied with your subscription, you can contact us for further help. Contact must be made within 3 business days of your subscription purchase and your refund request will be subject for review.

Please Note: Refunds can never be provided more than 30 days after the initial purchase date regardless of your activity on the site.