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OLEMISS / BISC / BISC 336 / what is the purpose of central dogma?

what is the purpose of central dogma?

what is the purpose of central dogma?

Description

School: University of Mississippi
Department: BISC
Course: Genetics
Professor: Erik hom
Term: Fall 2016
Tags: dr.hom, Genetics, Bisc336, Punnett Squares, phenotypes, genotypes, mendelian genetics, non-Mendelian, epistasis, geneticdiseases, amino acids, Mitosis, and Meiosis
Cost: 50
Name: Genetics Test #1 Studyguide
Description: Dr. Hom Test #1 Punnett Squares Phenotypes, genotypes Mendelian and non-mendelian genetics Epistasis Genetic Diseases Amino Acids Mitosis and Meiosis
Uploaded: 09/12/2017
5 Pages 3 Views 4 Unlocks
Reviews


Written by: erica Padgett


what is the purpose of central dogma?



genetics test #1 Study guide

• Dr. Hom Bisc 330

Central Dogma the flow of genetic information in biological systems

via polymers-DNA, RNA, + proteins

methylation

transcription lepigenetics DNA

> RNA translation, Proteins reverse

Transcription (retro-viruses)

replication

Prions

Study Soup

replication

Short/long RNA'S

(epigenetics)

Studys

Chromosomes: prokaryotic-found in nucleoidj eukaryotic, found in nucleus

Centromere location designation diagram

Parm middle

metacentric

(short)

between middle + end submeta centric centromere close to end

acrocentric

at the end

(long)

*"count the hips to determine #of chromosomes

tudy SOUT

telocentric

Chromatid

\q-arme

*major groove size=229


Chromosomes are what?



*minoy groove sizes 12 man chromosome *one turne 34

SECOUD

Study soup

Human Genome DNA facts: - one piece of DNA is - meter long if stretched out - ONA must fit into 5 um of space in nucleus - DNA is compacted 200,000x - Heterochromatin: densly packed w/ lots of protein - luchromatin : fewer proteins, more exposed DNA - DNA wraps around a histone + form's a nucleosome before a chromatid Nitrogenous Bases: Don't forget about the age old question of nonrational models of decision making explain how managers actually make decisions

A-T 2 Hydrogen bonds

thymine Pyr

G C 3 Hydrogen bonds

cytosine) "Angels + God are pure + mighty"

(more stable)

2 rings

.) Stud

uracil 2 pvrimidines

Adenine z Purines quanine )

cytokinesis

Synthesis

prepargnon T

anOSAPNS

anos

DNA Packing: O Primary Structure → synthesis

secondary structure → folding ® tertiary Structure packing

o quatemany structure – interaction mitosis -Cell divisjon 2n2n


mitosis is what?



Prophase 7 main *know what happens

S+(62) +4 + 1

metaphase steps of during each phase!

preparation

anaphase i mitosis *

T

*cohesin:protein complex

mitosis telophase

that holds together sister sis) own stage; chromatids until they're

not a part of ready to separate meiosis: 2n+n (diploid ->haploid) mitosis ('twist ties") Prophase Don't forget about the age old question of alexei boulatov

meiosis I

meiosis I

I

- sister chromatids

-homologus chromosomes

- homoloqus chromosomes u separate

separate (disjunction

Synapse (pair)

- mom dad separate - 4 separate cells@end

- CYossing over/homologus

recombination in pachytene) Sperm- 4 working spermatozoa *synaptonemal complex Veeps non-sister chromosomes together

eaq-1209, 3 polar bodlies

So they can crossover

In+c-values: h-valve: # of chromosomes in a gamete's genome C-valve: content amount of DNA in gamete's. genome Mitosis

Meiosis UT Cuto 6 MI

G, S G2 Mitosis Cytokinesis G

26 4C 4C 4C 20 2c lc.

26 4C 4C 40. 2c 2c

an an an an

in an an ( 24h) an an If you want to learn more check out derrick gholston
Don't forget about the age old question of comm 1500 uga

(2n) in

In

mendelian genetics): Backcross: cross of a progeny + aparental genotype test cross: a cross w/ a homozygous recessive

dihybrid Cross

Punnet Square

Probability

"Rrx Rr

RrQqx RrQq.

RO R8 VQ ra

Rr

(IAM) Independent + Multiply

by 3:1phenotype RQ

19:33: 1 phenotype ex) snake eyes

IRIRRIR

4 1:2 2:1 4:2:1:2:1 (16)(/6)= 1/36

1:2:1 genotype Rol

genotype (E04) exclusive or add

ex) Ace or king

(4/52) + (4/52) = 8/52 = 2/3 chi square

Study

StudySou:

StudySoup

Studs

r Rrrr

de-n-1 X2= Conserve de trapected? We also discuss several other topics like bankrate simple savings calculator

Inon-classical mendelian genetics 1: incomplete dominance: blending intermediate phenotype Co-dominance: both alleles expressed phenotypically over dominance: the heterozygote is more fit that the homozygotes epistasis: when one gene locu's masks the phenotype of another Penetrance: Portion of population that actually exhibit the mutant phenotype expressivity degree in which the mutant phenotype is expressed

Pedigree rules

0=female = mall -unknown D-carrier Ø-dead A= twins -- mating = = inbreeding autosomal dominant: no generation Skipping, can be

can be AA or Aa + show phenotype 50%. affectel autosomal recessive: carriers, 257 are affected

ed aominant: females > males, male--all daughters, affected sons have affected mom X-linked recessive malos females, affected males have heterozygous mom or affected mom y-linked: only male to male transmission mitochondrial: inherited from mom, 50/5020", Fz='superx dominant"

Lepistasis:

Study Soup

Biochemical Pathway regulatory/signalling outcomel I genet? 2 gene B 3 condition in genel geneza

outcome 2

dominant Epistasis : (12:3:1phenotype ratio recessive: (6:4:3) duplicate recessive:(937) duplicate aines w cummulahve effect:(9:6:1) duplicate dominant: (15:1) dominant i recessive: (13:3) Blood typing! A+B: two different types of agglutinocens +/-: has or doesn't have the Rh protein Mom If you want to learn more check out fiu bot

alleles

bloodtype

I

BO

A AA AB AO

Ato

AB *both types of surface molecules

8 B BA BB BO

A+B

BAB

оор о 00

BtO

oto

O no Surface molecules

Diseases Discussed: sickle cell anemia: glutamate-> Valine; chromosome ligene; clumps in artenes/veins Huntington's Disease: autosomal dominant; neurodegenerative; chromosome 4 > Ituntington protein

adult on set + early on-Set Klinefelter Syndrome: XXy; 47 chromosomes; only 851. of the Xis inactwated Turner Syndrome: X; 45 chromosomes; lacks extra par region Autism: autistic scale is based on epigenetics → expressivity

StudySoup

ATA

Study Soup

DOO

Wolbachial: Wolbachia: a bacterial endosymbiont (intracellular) that infects sex-cells + distorts

o in populations feminization: all offspring are female Parthenogenesis: the females do not need a male to reproduce; female offspring male killing the genes kill the males. cytoplasmic incompatability: when an unaffected male + an affected female

mate, all the offspring die haploid-diploid sex determination females-diploid; males= haploid amino acids):

Study

ady SOURO

udysozov

"OH

"OH

NIL

NHL

он

glycine, 6

alanine, A

Valine, v.

glutamic acid, E

pka=4.1

StudySoup

OH

OH

Sud OUT

NH2

Asparaigne, N

glutamine, a

aspartic acid, D

leucine, L

X

"OH

OH HOX OH H

OH

X

OH

NH2

NH2

NH2

cysteine, C

methionine, M.

serine, s

isoleucine, I

threonine, T

studySoup

Study Soup

StudySoup

StudySoup

PIS

Written by: erica Padgett

genetics test #1 Study guide

• Dr. Hom Bisc 330

Central Dogma the flow of genetic information in biological systems

via polymers-DNA, RNA, + proteins

methylation

transcription lepigenetics DNA

> RNA translation, Proteins reverse

Transcription (retro-viruses)

replication

Prions

Study Soup

replication

Short/long RNA'S

(epigenetics)

Studys

Chromosomes: prokaryotic-found in nucleoidj eukaryotic, found in nucleus

Centromere location designation diagram

Parm middle

metacentric

(short)

between middle + end submeta centric centromere close to end

acrocentric

at the end

(long)

*"count the hips to determine #of chromosomes

tudy SOUT

telocentric

Chromatid

\q-arme

*major groove size=229

*minoy groove sizes 12 man chromosome *one turne 34

SECOUD

Study soup

Human Genome DNA facts: - one piece of DNA is - meter long if stretched out - ONA must fit into 5 um of space in nucleus - DNA is compacted 200,000x - Heterochromatin: densly packed w/ lots of protein - luchromatin : fewer proteins, more exposed DNA - DNA wraps around a histone + form's a nucleosome before a chromatid Nitrogenous Bases:

A-T 2 Hydrogen bonds

thymine Pyr

G C 3 Hydrogen bonds

cytosine) "Angels + God are pure + mighty"

(more stable)

2 rings

.) Stud

uracil 2 pvrimidines

Adenine z Purines quanine )

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