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UA - PHYI 201 - Class Notes - Week 6

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UA - PHYI 201 - Class Notes - Week 6

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background image 12 February 2018
Lecture 12
Bone Growth and Remodeling There are two types of cartilage growth: Interstitial growth * Appositional growth * Interstitial Growth: Means “growing from within” Only occurs within the cartilage, not in bone Growth in length of the epiphyseal plate* Interstitial Growth Process: The chondroblasts* help build up the cartilage matrix*, and then becomes
chondrocytes*
The chondrocytes divide themselves ■ The chondrocytes continue to build the matrix; push apart to  create space/ separate from each other→ This is what makes the
cartilage tissue grow from the inside
*Diaphysis→ grows in length; epiphyseal plate does not change (childhood) Appositional Growth: Means “growth at the edges” Occurs in cartilage AND in bone Increases diameter of the bone Cortical width* increases Medullary cavity* size also increases as a result Appositional Growth Process: Periosteal (outer) osteogenic cells* differentiate into osteoblasts The osteoblasts* build bone on outside of bone ● Endosteal osteoclasts* increase marrow cavity diameter→  increases bone diameter, cortical width, and medullary 
cavity
The epiphyseal plate* growth helps with growth in width The plate itself does not grow, but the bone does as the cartilage builds Growth at the Epiphyseal Plate ● Osteoclasts begin to breakdown the calcified* cartilage→ creates room for the osteoblasts Osteoblasts build up the spongy bone Chondrocytes continue forming cartilage matrix in proliferating cartilage* area.

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School: University of Arizona
Department: Physiology
Course: Human Anatomy and Physiology I
Professor: Stanescu
Term: Spring 2016
Tags: Physiology
Name: Bone Growth and Remodeling
Description: Lecture 12 focuses on the process that forces bones to grow
Uploaded: 02/20/2018
2 Pages 18 Views 14 Unlocks
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