×
Log in to StudySoup

Forgot password? Reset password here

OSU - MICRBIO 4000 - Class Notes - Week 10

Created by: Grace Campbell Elite Notetaker

Schools > Ohio State University > Microbiology > MICRBIO 4000 > OSU - MICRBIO 4000 - Class Notes - Week 10

OSU - MICRBIO 4000 - Class Notes - Week 10

School: Ohio State University
Department: Microbiology
Course: Basic and Practical Microbiology
Professor: Tammy Madhura Pradhan
Term: Summer 2015
Tags: Microbiology and Biology
Name: Microbio 4000- Chapter 14 Notes
Description: These notes cover everything that was gone over in lecture on Chapter 14: The Innate Immune Response and all relevant Top Hat and review questions
Uploaded: 03/26/2018
This preview shows pages 1 - 4 of a 20 page document. to view the rest of the content
background image Chapter 14: The Innate Immune Response    A. Immune System: Innate and Adaptive Immunity  a. Immune system​ - internal device mechanism against pathogens  i. Innate immune system  1. Immediate, nonspecific​ response 
2. EX: skin, mucus membranes 
a. We’re born with it (germline encoded) 
b. Blocks bacteria and viruses in the same way 
(nonspecific)  3. Germline encoded 
4. No learning process or memory 
a. React every time as if it’s the first time  5. Consists of 3 components:  a. First-line defenses​: block entry  i. Internal and external borders  b. Sensor systems​: detect invasion 
c. Innate effector actions​: destroy invader  
i. Second-line defenses  ii. Destroys anything that was able to infiltrate  ii. Adaptive immune system  1. Acquired ​specific​ immunity 
2. Develops throughout life 
3. Specific​ recognition and memory  
4. EX: antibodies  
B. The Innate Immune System  a. BLOCK: first line defenses are ​barriers blocking entry  i. Security walls  ii. Prevent microbial entry  iii. EX: skin and mucus membranes  iv. Antimicrobial substances  b. DETECT: if invaders breach, sensor systems detect  i. Security cameras  ii. Detect damage and microbial invasion  iii. Pattern recognition receptors (PRRs)  iv. Complement system  c. DESTROY: innate defenses work to ​destroy invaders   i. Security teams  ii. Eliminate threat/invader  iii. Interferon response, phagocytosis, complement activation, inflammatory 
response, fever  
C. First line defenses (BLOCK) 
background image
background image
background image

This is the end of the preview. Please to view the rest of the content
Join more than 18,000+ college students at Ohio State University who use StudySoup to get ahead
20 Pages 71 Views 56 Unlocks
  • Better Grades Guarantee
  • 24/7 Homework help
  • Notes, Study Guides, Flashcards + More!
Join more than 18,000+ college students at Ohio State University who use StudySoup to get ahead
School: Ohio State University
Department: Microbiology
Course: Basic and Practical Microbiology
Professor: Tammy Madhura Pradhan
Term: Summer 2015
Tags: Microbiology and Biology
Name: Microbio 4000- Chapter 14 Notes
Description: These notes cover everything that was gone over in lecture on Chapter 14: The Innate Immune Response and all relevant Top Hat and review questions
Uploaded: 03/26/2018
20 Pages 71 Views 56 Unlocks
  • Better Grades Guarantee
  • 24/7 Homework help
  • Notes, Study Guides, Flashcards + More!
Join StudySoup for FREE
Get Full Access to OSU - MICRB 4000 - Class Notes - Week 10
Join with Email
Already have an account? Login here