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AU - NTRI 2000 - Class Notes - Week 6

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AU - NTRI 2000 - Class Notes - Week 6

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background image Class Notes 4/3/2018 Thiamin (Vitamin B-1) Coenzyme form used in energy (carbohydrate) 
metabolism
o Thiamin pyrophosphate (TPP) Deficiency: Beriberi o “I cant, I cant”
o Symptoms
Weakness, loss of appetite, irritability, poor 
extremity coordination, muscle pain
o From excess consumption of polished rice &  alcohol abuse  RDA o 1.1 mg/day for women; 1.2 mg/day for men
o Most exceed RDA in diet 
o Excess is rapidly excreted in urine; non-toxic 
Food sources: o Whole grains, ready-to-eat breakfast cereals Riboflavin (Vitamin B-2) Functions: o Coenzyme forms participate in energy-yielding  metabolic pathways these coenzyme forms carry
electrons 
Flavin adenine dinucleotide (FAD) Flavin mononucleotide (FMN) o Indirect antioxidant properties Glutathione peroxidase (GPX) o Homocysteine and some vitamin and mineral  metabolism  Deficiency: ariboflavinosis o Cheilosis (cracking around the mouth, lips, and  tongue), sensitivity to sun RDA o 1.1 mg/day for women; 1.3 mg/day for men
o Average intake above RDA
Found in milk, milk products, enriched 
grains/cereal, liver
Niacin (Vitamin B-3) Coenzyme forms used in energy metabolism these 
coenzyme forms carry electrons
o Nicotinamide adenine dinucleotide (NAD)
o Nicotinamide adenine dinucleotide phosphate 
(NAPD)
background image Niacin can be synthesized from the AA tryptophan  o 60 mg tryp = 1 mg niacin  Deficiency: o Pellagra Consequences Early o Poor appetite, weight loss,  weakness Late (4 D’s) o Dementia, dermatitis, diarrhea
o Death
At risk: Alcoholics Genetic disorder of tryptophan 
metabolism 
Food sources Enriched grains & cereals, Beef, 
Chicken/Turkey
Toxicity High dose niacin (>100 mg, such as in
supplements) can cause headache, 
itching, and flushing of the skin
o Blood vessel dilation resulting in increased blood flow  Have formulated delayed-release 
tablets because  High dose niacin 
beneficial for lowering blood lipid 
levels 
Pantothenic Acid Part of Coenzyme-A o Coenzyme-A essential for metabolism of  carbohydrate, protein, & fat (both synthesis and 
degradation)
Deficiency rare o Usually in combination with deficiencies of other  vitamins  No toxicity known o Food sources Milk, mushrooms, liver, peanuts, sunflower 
seeds 
Biotin Exists in a free and bound form in food o Raw egg whites – bound to avidin 

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School: Auburn University
Department: Nutrition and Food Sciences
Course: Nutrition and Health
Professor: Ramesh Jeganathan
Term: Summer 2015
Tags:
Name: Nutrition Class notes 4/3/2018
Description: These notes cover information discussed in class on 4/3/2018.
Uploaded: 04/03/2018
4 Pages 33 Views 26 Unlocks
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