Biochemistry Dr. Krauss
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Week 17 Transcription
Genes are not used until transcribed and expressed
Introns – portion of the gene not expressed into a protein
Exons – portion of the gene that is expressed into a protein
RNA polymerase unwinds DNA and transcribes into RNA
Contains 5 subunits
Transcription begins upstream
A hairpin structure indicates termination of transcription
See page 1048 to see RNA processing
Some introns splice themselves
See pages 10511058 for the processing and splicing methods. This material is hard to put into words, so diagrams are used well
RNA Processing and Modification
Bacterial mRNAs do not undergo any significant form of processing; the primary transcript that is synthesized is itself the mature mRNA, and its translation usually begins before the transcription is complete
Eukaryotic mRNA synthesis is fundamentally similar to bacterial mRNA transcription, but eukaryotic transcription is processed far more
Eukaryotic mRNAs are processed as they are being synthesized, and that 5’ cap (7 methyl guanosine) is added as soon as initiation begins If you want to learn more check out What is the study of matter?
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If you want to learn more check out Define operant conditioning.
The termination of mRNA synthesis is due to polyadenylation
Spliceosome – the proteinRNA complex involved in splicing GUAG or AUAC introns As previously state, transcription and translation each are processes difficult to explain and it is advised to view diagrams and videos on the subjects