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This 1 page Study Guide was uploaded by Renee Lehner on Wednesday September 9, 2015. The Study Guide belongs to BIOL 411 at University of Washington taught by Staff in Fall. Since its upload, it has received 15 views. For similar materials see /class/192341/biol-411-university-of-washington in Biology at University of Washington.
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Date Created: 09/09/15
BIOL 411 HONORS THIRD EXAM STUDY QUESTIONS December 1 2008 1 Presentation by Sarah Mamman Myf5 and it s role in Mouse Skeletal Muscle Regeneration How were the mice muscles injured in this study What was the phenotype ofthe regenerated muscle in the Myf5 knockout mice What did the authors conclude from this study Do you think that their conclusions were justified What do you think the researchers should do 2 Presentation by Adam Mina Targeted Disruption of Cardiac Troponin T Describe how the researchers knocked out the cardiac troponin T gene in the experimental mice Did they get a complete knockout What was the phenotype of the mutant mice both at the cellular and at the embryonic level Is this what you would have expected Explain why or why not the knockout phenotype was what you expected based on the normal function ofthe protein in the sarcomere 3 Presentation by Rosie Lindeke FGF Effects on Heart Size and Specification Describe the importance of the ACE mutant zebrafish to these studies What was the phenotype ofthe mutant fish both at the cellular and at the embryonic level How did the drug SU5402 allow a more precise understanding of when FGF signaling was important during developmental processes What were the authors conclusions December 3 2008 1 Explain the basis for thalidomidedependent teratogenicity during vertebrate limb development What societal or biomedical lessons can be learned from the events of the late 1950s and early 1960s 2 Explain the role of methylation in the etyology of neural tube malformations 3 What is the difference between XY and VVZ mechanisms of sexdetermination Which organisms employ which modes
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