×
Log in to StudySoup
Get Full Access to RP - APSC 332 - Class Notes - Week 3
Join StudySoup for FREE
Get Full Access to RP - APSC 332 - Class Notes - Week 3

Already have an account? Login here
×
Reset your password

RP / Applied Science / APSC 332 / What is the formation of a polypeptide chain?

What is the formation of a polypeptide chain?

What is the formation of a polypeptide chain?

Description

School: Republic Polytechnic
Department: Applied Science
Course: Structural Biology
Professor: Sun wen
Term: Fall 2015
Tags:
Cost: 25
Name: Structural Biology
Description: Formation of a polypeptide chain:      Terminus:  ­ C terminus  ­ Each polypeptide chain starts on the right side by free COOH group of the  last amino acid  ­ N terminus  ­ Each polypeptide chain starts on the left side by free amino group of the first  amino acid enter in chain formation    General colour code:  ­ Hydrogen → White  ­ Oxygen → Red  ­ Nitrogen → Blue    Peptide:  ­ Amino acids join
Uploaded: 11/08/2015
4 Pages 67 Views 1 Unlocks
Reviews


Formation of a polypeptide chain: 


What is the formation of a polypeptide chain?



Terminus: 

­ C terminus

­ Each polypeptide chain starts on the right side by free COOH group of the last amino acid

­ N terminus

­ Each polypeptide chain starts on the left side by free amino group of the first amino acid enter in chain formation

General colour code: 

­ Hydrogen → White

­ Oxygen → Red


What is the general colour code for nitrogen?



­ Nitrogen → Blue

Peptide: 

­ Amino acids join together to form peptide

­ Chain

­ >10 amino acids

­ referred as polypeptide

­ > 50 amino acids

­ referred as protein

Cause of Disease: 

Point mutation → Protein sequence change → structural change → functional change → disease

Types of forces: 

­ Van der Waal’s interactions


What is the distance of hydrogen bonds?



We also discuss several other topics like What is the difference between meiosis and mitosis?

­ Temporary bond

­ When two atoms are close to each other

­ Larger surface area → stronger

­ Individually → weak

­ Structure → must be very close

­ Strength: 0.4 ­ 4.0 kJ/mol

­ Distance: 0.3 ­ 0.6 nm

­ Hydrogen bonds

­ Can occur in polar side chain amino acid except cysteine

­ Carbonyl group and amide group can form hydrogen bond

­ Strength: 5 ­ 30 kJ/mol

­ Distance: 0.3 nm

­ Ionic Interaction

­ Only one charged side chain can form ionic bond

­ Strength: 140 ­ 250 kJ/mol

­ Distance: 0.25 nm

­ Hydrophobic interaction

­ Two nonpolar interact

­ Strength: <40 kJ/mol

­ Distance: varies

­ Disulfide bond

­ S­S bond

­ Strength: 266 kJ/mol

­ Distance: 0.2 nm

­ Peptide bond

­ C­N bond

­ Covalent bond Don't forget about the age old question of Concerning identity formation during one's lifetime, the "mama" cycle refers to?

­ 10 fold stronger than hydrogen bond

­ Strength: 305 kJ/mol

­ Distance: 0.13 ­ 0.147 nm

Protein Structures: 

Proteins are polymers constructed from the same set of twenty different amino acids. ­ Primary Don't forget about the age old question of When merchandise is returned to the seller and the seller uses a perpetual inventory system, what account decreases?

­ It is the specific sequence of amino acids specified by the gene

­ Secondary

If you want to learn more check out How many chromosomes do humans have?

This is a picture of how beta sheets look like

­ The structure portion to the protein begin to fold in a three­dimensional formation

­ Folds and coils of the protein are the result of hydrogen bombs that occur in regulat intervals

­ There are two kinds of structure

­ Alpha helix

­ Beta pleated sheets

­ Tertiary

­ Formed by interactions between side chains of various amino acids ­ Some proteins may be completed

­ Quaternary

We also discuss several other topics like What are the three levels of personal dispositions?

The left picture is collagen and the right picture is haemoglobin ­ Proteins that incorporate multiple polypeptide subunits If you want to learn more check out What primary hormone involved in plasma ca2+ concentration ?

20 Types of amino acids:

Page Expired
5off
It looks like your free minutes have expired! Lucky for you we have all the content you need, just sign up here