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UND - PHSL 301 - Study Guide

Created by: Lexie Stenson Elite Notetaker

UND - PHSL 301 - Study Guide

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background image PHARMACOLOGY EXAM 3 ATORVASTATIN Trade Name: Lipitor Therapeutic Class: Antihyperlipidemic Therapeutic Use: Reduction of LDL and cholesterol Pharmacologic Class: HMG-CoA reductase inhibitor Mechanism of Action: Reduction of synthesis of cholesterol in the liver; 
increase in LDL receptors in the liver
CHOLESTYRAMINE Trade Name: Questran Therapeutic Class: Antihyperlipidemic Therapeutic Use: Reduction of cholesterol Pharmacologic Class: Bile acid rain resin Mechanism of Action: Prevent enterohepatic recycling of bile acids, 
increasing elimination of cholesterol
EZETIMIBE Trade Name: Zetia Therapeutic Class: Antihyperlipidemic Therapeutic Use: Adjunct to therapy with statin to reduce LDL Pharmacologic Class: Cholesterol absorption inhibitor Mechanism of Action: Inhibits intestinal absorption of cholesterol GEMFIBROZIL Trade Name: Lopid Therapeutic Class: Antihyperlipidemic Therapeutic Use: To reduce triglycerides and VLDL, to increase HDL Pharmacologic Class: Fibric acid agent Mechanism of Action: Decreases conversion of cholesterol to VLDL, and 
increase lipoprotein lipase synthesis
NICOTINIC ACID (VITAMIN B) Trade Name: Niaspan
background image Therapeutic Class: Antihyperlipidemic Therapeutic Use: Treatment of hyperlipidemia not responding to diet and 
weight loss; to slow progression of coronary artery disease (CAD) when 
combined with a bile acid sequestrant
Pharmacologic Class: Other antihyperlipidemics; vitamin Mechanism of Action: Inhibits release of free fatty acids from adipose tissue, 
increases rate of triglyceride removal of plasma, reduces LDL and 
triglyceride levels and increases HDL levels
DOXAZOSIN Trade Name: Cardura Therapeutic Class: Antihypertensive; treatment of benign prostatic 
hyperplasia (BPH)
Therapeutic Use: To treat hypertension; treatment of BPH Pharmacologic Class: Alpha-1 adrenergic blocker Mechanism of Action: Selective for alpha 1 adrenergic receptors, thus causes
vasodilation; also causes relaxation of smooth muscle around the prostate 
gland
ENALAPRIL Trade Name: Vasotec Therapeutic Class: Antihypertensive; treatment of heart failure Therapeutic Use: To treat hypertension; treatment of heart failure Pharmacologic Class: ACE inhibitor Mechanism of Action: Inhibits conversion of angiotensin I to angiotensin II, a 
vasoconstrictor, and decreases production of aldosterone, resulting in 
decreased renal sodium absorption
HYDRALAZINE Trade Name: Apresdline Therapeutic Class: Antihypertensive; treatment of heart failure Therapeutic Use: Treatment of hypertension that is refractory to other 
antihypertensive
Pharmacologic Class: Direct-acting inhibitor Mechanism of Action: Relaxes arterial smooth muscle by inhibiting IP3 
formation
background image HYDROCHLOROTHIAZINE Trade Name: Microzide Therapeutic Class: Antihypertensive; treatment of edema Therapeutic Use: To treat hypertension with edema; also approved to treat 
heart failure, and nephrotic syndrome
Pharmacologic Class: Thiazine diuretic Mechanism of Action: Decreases reabsorption of sodium in the kidney by 
inhibiting the sodium/chloride cotransporter in the distal tube of the nephron
NIFEDIPINE Trade Name: Adalat Therapeutic Class: Antihypertensive; treatment for angina Therapeutic Use: To treat hypertension and variant or vasospastic angina Pharmacologic Class: Calcium channel blocker Mechanism of Action: Selectively blocks calcium channels in myocardial 
muscle and vascular smooth muscle
ATENOLOL Trade Name: Tenormin Therapeutic Class: Antianginal; antihypertensive Therapeutic Use: Treatment of heart failure, hypertension, angina, and MI Pharmacologic Class: Selective beta1-adrenergic blocker Mechanism of Action: Selectively blocks beta1-adrenergic receptors in the 
heart; slows heart rate and reduces contractility
LOSARTAN Trade Name: Cozaar Therapeutic Class: Antihypertensive Therapeutic Use: Used alone or in combination therapy for treatment of 
hypertension; treatment of diabetic nephropathy
Pharmacologic Class: Angiotensin II receptor blocker Mechanism of Action: Selectively blocks angiotensin II receptors; blocks 
vasoconstriction, and release of aldosterone due to interruption of the renin-
angiotensin-aldosterone system
background image PROPANOLOL Trade Name: Inderal Therapeutic Class: Class II antidysrhythmic; antihypertensive Therapeutic Use: Treatment of cardiac dysrhythmia, hypertension, angina, 
and migraine headaches, and for prevention of MI
Pharmacologic Class: Beta-adrenergic antagonist (nonselective) Mechanism of Action: Nonselective beta-adrenergic blocker; affecting beta1 
receptors in the heart, and beta2 receptors in pulmonary and vascular 
smooth muscle; reduces heart rate, slows myocardial conduction velocity, 
and lowers BP
DIGOXIN Trade Name: Digitek Therapeutic Class: Positive inotrope Therapeutic Use: To increase cardiac output, alleviating symptoms of heart 
failure and improving exercise tolerance
Pharmacologic Class: Cardiac glycoside Mechanism of Action: Inhibits Na-K+ ATPase, and increases intracellular 
calcium concentrations in cardiac cells
FUROSEMIDE Trade Name: Lasiz Therapeutic Class: Antihypertensive, treatment or edema and heart failure Therapeutic Use: Treatment of acute heart failure, to remove edema, 
especially when cardiac output and renal flow are severely diminished
Pharmacologic Class: Loop diuretic Mechanism of Action: Prevents renal absorption of Na and Cl in the loop of 
Henle
LISINOPRIL Trade Name: Prinivil Therapeutic Class: Antihypertensive, treatment for heart failure Therapeutic Use: Treatment of hypertension, heart failure, and improvement 
of survival in patients when administered within 24 hours after MI
Pharmacologic Class: ACE inhibitor Mechanism of Action: Inhibits angiotensin converting enzyme, decreasing 
aldosterone secretion

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School: University of North Dakota
Department: Physiology
Course: Human Physiology
Professor: James Haselton
Term: Spring 2016
Tags: pharmacology, pharm, meds, Nursing, memorize, color code, easy, PPT 301, and UND
Name: Pharmacology PPT 301 Exam 3 Notes
Description: Hi! This is the study aid terms from the online section in Blackboard. I have color coded everything and once you open this it will become much more obvious what I have done to help in the study process! I find these to be extremely helpful in guiding my thoughts when trying to study for this class!
Uploaded: 03/30/2016
15 Pages 14 Views 11 Unlocks
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