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Week 1 Molgen Notes

by: Mallory McMullen

Week 1 Molgen Notes 4606

Marketplace > Ohio State University > 4606 > Week 1 Molgen Notes
Mallory McMullen
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About this Document

These notes cover Dr. Chamberlin's Mon/Weds/Fri lectures this week, minus Monday because we were just doing introductory activities
Molecular Genetics
Dr. Chamberlin
Class Notes




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This 2 page Class Notes was uploaded by Mallory McMullen on Friday January 15, 2016. The Class Notes belongs to 4606 at Ohio State University taught by Dr. Chamberlin in Spring 2016. Since its upload, it has received 70 views.


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Date Created: 01/15/16
Wednesday, January 13, 2016 Cell Cycle▯ Molgen 1/11-1/15/16 - In G-0 the cell is non-dividing▯ - After the G1/S checkpoint the cell is committed to dividing▯ - M Checkpoint= spindle assembly ▯ • Makes sure you have equal tension before separating the chromosomes▯ - Biosynthesis is regulatory via the checkpoints▯ - A cell is only gonna go through the process of DNA replication and growth if it is confident it will divide▯ -When 4N is larger we can assume that the cell is spending more of its time in G2 ▯ -Cohesin: keeps sister chromatids together in metaphase▯ •An enzyme breaks down cohesion during anaphase ▯ • Without cohesin the spindles would pull apart the chromatids before they’re lined up and you might have an uneven number of chromosomes in the new cell▯ Mitosis vs. Meiosis▯ Similarities Differences Similar steps (pro/meta/ana/telophase) 2 identical cells vs. 4 haploid cells Equational division Somatic vs. gametes Pairing of homologous chromosomes 1 Wednesday, January 13, 2016 - Allele: a representation of a gene▯ - If something failed during step 2 (meiosis II) we would have 3 cells: 2- a+ and 1- aa▯ - If something failed during step 1 (meiosis I) we could get a combination of a/a+ cells ▯ - It’s important for cells to produce these gametes to preserve the genetic information throughout the generations▯ - Diploid organism: carries 2 copies of each chromosome; one from each parent▯ • In a heterozygous individual with n=2, its cells in meiosis I would look like C; meiosis II would look like D; and mitosis would look like F▯ 2


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