BMS260Week1notes.pdf BMS 260
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Popular in Biomedical Sciences
This 3 page Class Notes was uploaded by Mikaela Maldonado on Sunday January 24, 2016. The Class Notes belongs to BMS 260 at Colorado State University taught by Dr. Russell Anthony in Spring 2016. Since its upload, it has received 82 views. For similar materials see Biomedical Sciences in Biomedical Sciences at Colorado State University.
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Date Created: 01/24/16
oz Wednesday Notes Lecture 1 oz Introduction and Cells oz Microscopic ATOMS make up MOLECULES that make up PROTEIN FILAMENTS or ORGANELLES that make up CELLS that make up TISSUES that make up ORGANS oz Gross levels ORGANS make up BODILY ORGAN SYSTEMS such as Integumentary skeletal muscular nervous endocrine cardiovascular lymphatic respiratory digestive urinary reproductive All of this makes the ORGANISM The cell cycle has 4 main parts GlgtSgtGzgtMgtGl O O 90 90 oz Biosynthetic simple things are made into bigger things like macromolecules 61 phase aka growth phase o Makes stuff for the components of DNA to be synthesized in S phase 9 5 hours long o Antimetabolites can stop the cells from making the stuff to build into DNA Gz phase guess what A growth phase 9 Makes stuff for cell division 9 3 hours long o microtubule inhibitors stop things from being made here M phase 9 The cell divides o 1 hour Most of the cells go to rest in G0 phase but some pass back into 61 9 Cannot be stopped 393 NOT biosynthetic S phase o DNA synthesis aka replication 9 7 hours o Agents that bind to DNA can stop replication oz Plasma Membrane Dynamic regulatory barrier can change and adapts to regulate homeokinesis almost like homeostasis but actually is quotachievement of equilibrium in body functions by dynamic processquot taken from the medical dictionary online through the freedictionarycom Composed of a phospholipid bilayer O O O Fluid mosaic model goes back to dynamic regulatory barrier Singer and nickolson 1972 gt The model was proposed to describe the structure of cell membranes as the uid mosaic model gt The membrane contains lots of things Proteins cholesterol channels etc Polar head groups hyrophillic and charged Non polar tails fatty acid chains hydrophobic Fatty acids gt Saturated fatty acids no double bonds in structure E gt Unsaturated fatty acids double bonds in structure makes the membrane more uid why Structure can be more loosely packed allowing more movement Q This is the double bond rig theregt O Proteins gt lntegral proteins anchored in plasma membrane gt Peripheral proteins not anchored directly into the plasma membrane allows for cells to interact and receive signals from outside the cell Desmosomes gt Cadherins interact between the cells Gap between cells is 20 nm space that allows movement between cells Paracellular movement can occur between the cells Strong attachments o Tight junctions gut epithelium gt Touching but not actually locked together gt Transcellular has to go inside the cell to pass to the other side 9 Gap junctions gt 15 nm diameter channels that join the cytosol of cells side by side gt communicate and coordinate between cells 9 Transport gt Diffusion Movement from high concentration to low concentration gt Facilitated diffusion Movement from high to low concentration with the assistance of a protein for example gt Active transport Solutes move from low to high concentration requires energy and requires something to make the movement possible F day CHECK OUT CANVAS FOR GUEST SPEAKER LECTURE too good to even try to copy l
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