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Patho I Pre-Exam Notes

by: Haley

Patho I Pre-Exam Notes NURS 239 001

GPA 3.5

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About this Document

The latest lecture notes from the Monday before the exam.
Pathophysiology I
Class Notes
pathophysiology, patho, Nursing, health, inflammation
25 ?




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This 3 page Class Notes was uploaded by Haley on Tuesday February 2, 2016. The Class Notes belongs to NURS 239 001 at University of New Mexico taught by Drexler in Fall 2015. Since its upload, it has received 21 views. For similar materials see Pathophysiology I in Nursing and Health Sciences at University of New Mexico.

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Date Created: 02/02/16
Patho I Pre­Exam Notes  Manifestations of Inflammation  Local: effects area of injury  Systemic: effects entire body  heat  fatigue, lethargy  pain  fever, headache  edema: swelling  weight loss  incapacitation: body part is not  increased circulation  functional    increased leukocytes and plasma  proteins in blood    How to treat inflammation:  ● RICE→ reduce blood flow and swelling  ● Anti‐histamines→ block chemical mediators  Why should we treat it?  ● More tissue damage can occur past the area of immediate damage.  ● The less time the body is under inflammation, the better.  Chronic Inflammation  ● Lasts 2+ weeks  ● Occurs without acute inflammatory process  ● Granuloma: the body walls off damaged tissue  ○ Swollen knuckles  Tissue Healing  ● Inflammatory phase  ○ Wound area is cleaned  ○ Fibrin mesh is laid down   ● Proliferative phase  ○ Collagen mesh  ○ Scar tissue  ○ Cell differentiation begins  ● Remodeling phase  ○ Fibroblasts complete scar  ○ Cells finish differentiating   ● Primary intention: wound is closed with sutures or adhesion process  ● Secondary intention: wound heals naturally   ○ Bowl shape from the bottom up  ● Angiogenesis: new blood vessel creation  Complications of Tissue Healing  ● Ulceration: cells don’t have anything to build next to so they erode themselves  ● Infection: a bacteria lodges itself in the wound while it is healing. Then, it  multiplies and breaks the wound open again so the process must start over.  ● Dehiscence: Wound opens due to internal pressure  ○ Abdominal sutures burst when patient uses abs  ● Keloids: Overproduction of scar tissue  ● Adhesions: stalactite/mite formations that attach to walls to heal  Gastritis  ● Type of acute inflammation  ● Not getting enough good blood flow to the stomach  ● Endothelial lining of stomach is damaged because HCl erodes tissue   ○ acid+ acid= gastric irritation  ● H. pylori: bacteria that eats through tissue  ● Symptoms:   ○ Relux: undergoes hyperplasia  ○ Nausea  ○ Vomiting   ○ Loss of appetite   ○ Pain  ● Diagnostic  ○ Endoscope  ○ Stool Sample  ○ What color is poop/vomit?  ○ What did they eat?  ○ Blood count to test for anemia  ● Treatment  ○ Buffer acid with base→ Tums, Ca based medication  ○ Get rid of substance causing irritation         Crohn's  Ulcerative Colitis   Skip lesions  Continuous lesions  Small intestine  Large intestine (colon)  Colon pain  Sigmoid colon and rectum  Camera pill  Crampy pain  MRI/CT scan  Colonoscopy   Smoking cessation  Nutritional consult  Pinkish ring in toilet water  Take anti‐inflammatories  Test for occult blood  Blood stools  Fever, weight loss, fatigue      Endemic: disease or condition that is regularly found in an area  Pandemic: worldwide or nationwide disease  Epidemic: disease in a community at a certain time   


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