Popular in General Biology 1
Popular in Biochemistry
This 2 page Class Notes was uploaded by Ernie on Sunday February 7, 2016. The Class Notes belongs to BIO 181 at Arizona State University taught by Chakravadhanula, Farrokh, Konikoff in Winter2015. Since its upload, it has received 35 views. For similar materials see General Biology 1 in Biochemistry at Arizona State University.
Reviews for Bio 181
Report this Material
What is Karma?
Karma is the currency of StudySoup.
You can buy or earn more Karma at anytime and redeem it for class notes, study guides, flashcards, and more!
Date Created: 02/07/16
Bio Notes 2/3/2016 Clicker Questions 1. B 2. A 3. E 4. A 5. B 6. D Cell Cycle Polymerase needs 3 prime OH to start Primer- Small nucleic acid that allows replication to begin PCR uses DNA as primer Cell Cycle checkpoints happen at various points end of G1 and G2 and during Metaphase in M phase to make sure that cell replication is going right Most time spent in G phases End of G1 checks for errors in DNA, this prevents mutations from passing on to daughter cells, G1 also checks that cells are large enough to replicate DNA RB Protein blocks progression at end of G1, if Phosphate is added to RB groups it allows it to pass RB suppresses tumors stops division of cells uncontrollably Tumors Benign- are safe Malignant- not safe because they spread to other body parts Cancer cells divide forever unlike normal cells defective cell cycle control BRCA1 & 2 help repair damaged DNA if they are mutated more likely to cause cancer Cancer usually has 6-9 mutations Many genes mutated in cancer are regulated in cell cycle Tumor Suppressors- Brakes to stop cell cycle Positive Regulators- Accelerators, over active or excessive growth Treating cancer can be done by block the growth factor receptor Transcription DNA to RNA RNA to Protein is translation Central Dogma- DNA to RNA to Protein/polypeptide Translation makes nucleic acids into amino acid codons When you don’t go from DNA to RNA to protein you are an exception of the central Dogma Reverse Transcription is making DNA from RNA HIV Flu and genes only making RNA are exceptions of Central Dogma When you deviate from central dogma they make mistakes a lot which is why flu is different every year One Gene codes for one protein USUALLY Very small fraction of Genome codes for actual protein most is “Junk DNA” DNA vs. RNA RNA has U not T RNA is single stranded RNA has extra Oxygen RNA polymerase needs to start at the beginning of a gene, This is why it binds to a promoter to start transcription Promoter- Where transcription initiates Elongating starts in 5-3 so it is read off of 3-5 prime RNA Polymerase does not proof read in transcription unlike DNA polymerase Terminator Site- The end of the gene that stops transcription
Are you sure you want to buy this material for
You're already Subscribed!
Looks like you've already subscribed to StudySoup, you won't need to purchase another subscription to get this material. To access this material simply click 'View Full Document'