Control of Gene Expression in Eukaryotes
Control of Gene Expression in Eukaryotes Bio 111
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This 1 page Class Notes was uploaded by Alisa A. on Monday February 15, 2016. The Class Notes belongs to Bio 111 at Adelphi University taught by in Winter 2016. Since its upload, it has received 43 views. For similar materials see Biological Concepts and Methods in Biology at Adelphi University.
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Date Created: 02/15/16
Chapter 19: Control of Gene Expression in Eukaryotes ● Eukaryote vs Prokaryote ○ Eukaryotic: Complex Cells, has a defined nucleus ● Differential Gene Expression: Why do we see certain RNA’s in certain cells ○ DNA, mRNA, RNA, Protein (Central Dogma) ■ Replication: DNA makes more DNA ■ Transcription: DNA makes RNA ■ Translation: RNA makes protein ○ DNA wound up tight, to have transcription occur it needs to open up. To do this we have chromatin remodeling so that the promoters and transcription factors can bind to the DNA. ○ Transcription occurs, forming initial RNA (made up of exons and introns) ○ RNA processing, where we splice (cut and remove the introns) and add a tail and cap. Splicing can cause different gene forms. ○ mRNA stability, can be broken down rapidly which can mean that they are not making much protein. If stable then can make a lot of protein. Leaves nuclear and enters cytoplasm. ○ Translation is the change into amino acid sequence, forming a polypeptide. ○ Post translational modification, when a protein gets folded into correct configuration.