New User Special Price Expires in

Let's log you in.

Sign in with Facebook


Don't have a StudySoup account? Create one here!


Create a StudySoup account

Be part of our community, it's free to join!

Sign up with Facebook


Create your account
By creating an account you agree to StudySoup's terms and conditions and privacy policy

Already have a StudySoup account? Login here

BIOL 5600 Notes 2/2/16

by: LaurenC

BIOL 5600 Notes 2/2/16 BIOL 5600

Marketplace > Auburn University > Biology > BIOL 5600 > BIOL 5600 Notes 2 2 16

Preview These Notes for FREE

Get a free preview of these Notes, just enter your email below.

Unlock Preview
Unlock Preview

Preview these materials now for free

Why put in your email? Get access to more of this material and other relevant free materials for your school

View Preview

About this Document

These notes cover muscle fiber physiology.
Biomedical physiology
Dr. Mendonća
Class Notes
25 ?




Popular in Biomedical physiology

Popular in Biology

This 2 page Class Notes was uploaded by LaurenC on Wednesday February 17, 2016. The Class Notes belongs to BIOL 5600 at Auburn University taught by Dr. Mendonća in Winter 2016. Since its upload, it has received 44 views. For similar materials see Biomedical physiology in Biology at Auburn University.


Reviews for BIOL 5600 Notes 2/2/16


Report this Material


What is Karma?


Karma is the currency of StudySoup.

You can buy or earn more Karma at anytime and redeem it for class notes, study guides, flashcards, and more!

Date Created: 02/17/16
BIOL 5600 2-2-16  T-tubule -Transverse tubule -Holds Ca+2 -Space around is called terminal cisternae >20% of Ca+2 comes from outside the cell >80% of Ca+2 comes from the terminal cisternae  VR Ca+2 pumps -To pump Ca+2 back out of cell -For re-establishment  Excitation -Contraction coupling  Release of neurotransmitters  Series of proteins that form snare complex 1) Synaptobrevin -On synaptic vesicle surface 2) Primary proteins -Syntaxin and snap 25 -Coming off of the axonal terminal membrane -Oriented inwardly 3) Synaptotagmin -Between synaptic vesicle and axonal terminal -Ca+2 sensitive *Snare complex is formed hen Synaptotagmin is induced by Ca+2 -Results in rupture of synaptic vesicle and endocytosis of Ach -Binding of Ach sends Na+ into the cell *There is always Achase in neuromuscular junctions  Detail of overall process -What happens at the T-tubules  A specialized compound that causes release of Ca+2 from terminal cisternae -Voltage sensitive protein called DHP receptor >Along the T-tubule >Mechanically regulated  VR Ca+2 channel beside t-tubule called RyR (Rynodine receptor)  Once released, Ca+2 binds in cell to troponin and rotates tropomyosin out of the way causing myosin heads (an ATPase)to bind actin and ATP -Stored potential energy -Low energy 1) Myosin heads pop up out of low energy and grab actin 2) Binding /Splitting of ATP 3) Power stroke 4) Myosin head binds new ATP -Back down to low energy  Muscle fiber -Some initial energy reserves o Inside muscle fiber 1) Myosin head- ATP -Each head has an ATP molecule associated with it -Powers few seconds of contraction 2) Creatine phosphate -30 seconds of contraction *Creatine NP (high energy group attached) donated to Pn ADP to form ATP 3) Glycogen -Storage form of glucose -Can be readily metabolized to form ATPs (Because it doesn’t come from anywhere) -Can go through metabolic pathways to make ATP by becoming glucose (C6H12O6) -Length depends on O2 levels in cell *Glycogen>glucose>glycolysis (splitting of glucose)>2 pyruvate molecules (C3H6O3)  Anaerobic metabolism -No O2 needed thus far -Krebs cycles produces a lot of ATP


Buy Material

Are you sure you want to buy this material for

25 Karma

Buy Material

BOOM! Enjoy Your Free Notes!

We've added these Notes to your profile, click here to view them now.


You're already Subscribed!

Looks like you've already subscribed to StudySoup, you won't need to purchase another subscription to get this material. To access this material simply click 'View Full Document'

Why people love StudySoup

Jim McGreen Ohio University

"Knowing I can count on the Elite Notetaker in my class allows me to focus on what the professor is saying instead of just scribbling notes the whole time and falling behind."

Allison Fischer University of Alabama

"I signed up to be an Elite Notetaker with 2 of my sorority sisters this semester. We just posted our notes weekly and were each making over $600 per month. I LOVE StudySoup!"

Bentley McCaw University of Florida

"I was shooting for a perfect 4.0 GPA this semester. Having StudySoup as a study aid was critical to helping me achieve my goal...and I nailed it!"

Parker Thompson 500 Startups

"It's a great way for students to improve their educational experience and it seemed like a product that everybody wants, so all the people participating are winning."

Become an Elite Notetaker and start selling your notes online!

Refund Policy


All subscriptions to StudySoup are paid in full at the time of subscribing. To change your credit card information or to cancel your subscription, go to "Edit Settings". All credit card information will be available there. If you should decide to cancel your subscription, it will continue to be valid until the next payment period, as all payments for the current period were made in advance. For special circumstances, please email


StudySoup has more than 1 million course-specific study resources to help students study smarter. If you’re having trouble finding what you’re looking for, our customer support team can help you find what you need! Feel free to contact them here:

Recurring Subscriptions: If you have canceled your recurring subscription on the day of renewal and have not downloaded any documents, you may request a refund by submitting an email to

Satisfaction Guarantee: If you’re not satisfied with your subscription, you can contact us for further help. Contact must be made within 3 business days of your subscription purchase and your refund request will be subject for review.

Please Note: Refunds can never be provided more than 30 days after the initial purchase date regardless of your activity on the site.