BIOE 1010 Week 7 Notes
BIOE 1010 Week 7 Notes BIOE 1010
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BIO E 302
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This 2 page Class Notes was uploaded by Sara Littlejohn on Thursday February 18, 2016. The Class Notes belongs to BIOE 1010 at Clemson University taught by Dr. Vladimir Reukov in Spring 2016. Since its upload, it has received 24 views. For similar materials see Biology for BioEngineers in Bioengineering at Clemson University.
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Date Created: 02/18/16
Module 4-2 Action Potential Bold Red Text- This material will be on exam Highlighted Text- important concept/term The structure of the neuron The Na/K pump uses the energy of ATP hydrolysis to pump Na+ out and K+ in, both against their electrochemical gradients. o Outside the pump is more positive, while inside the pump is negative. Ion channels have highly selective hydrophilic pores. o They make the membrane permeable for selected inorganic ions depending on: Diameter and shape of the channel Distribution of charged amino acids that line the channel o They have a HUGE transport rate because the protein doesn’t need to change conformation with each ion it passes o They are gated, which means they open in response to changes in membrane voltage. o They are essential for signaling in nerve cells. o These channels are only one way; neurons cannot transmit signal both ways. An action potential is triggered by a brief pulse of current (depolarizing stimulus). -Need to be able to label: Resting potential Depolarization Repolarization Action potential Threshold o Resting Potential is always around -60 through -70 mV Variation in the resting potential can be either inhibiting or excited. o Threshold is always around -55 mV o Action Potential is always around 40 mV
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