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Chapter 3 Pathology

by: Jaime Dolan

Chapter 3 Pathology 623359

Jaime Dolan
penn state berks

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About this Document

Main points of Chapter 3
Anatomy,Physiology, & Disease
Dr. John Grandizio
Class Notes
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This 3 page Class Notes was uploaded by Jaime Dolan on Sunday February 21, 2016. The Class Notes belongs to 623359 at penn state berks taught by Dr. John Grandizio in Winter 2016. Since its upload, it has received 47 views. For similar materials see Anatomy,Physiology, & Disease in Professional Education Services at penn state berks.

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Date Created: 02/21/16
Chapter 3 Pathology  Pathology is the study of disease ­abnormal function of the body results in disease ­loss of homeostasis, i.e abnormally functioning organs or organ systems resulting from a  disruption in the in the normal state of the body’s internal environment  ­disruption via malnutrition, external environment, genetic abnormalities to name a few Signs and Symptoms of Disease  ­pain­physical suffering or distress due to injury or illness  ­inflammation­the body’s immune response to injury and disease ­redness ­swelling  ­heat  Predisposing Factors of Disease ­predisposing factors are risk factors or activities that people participate in that can affect their  health (research)  Uncontrolled Factors ­age  ­heredity ­gender  ­congenital=present at birth ­genetic=inherited genes from parents  ­developmental=before, at, or after birth  ­controlled factors­lifestyles, environment  Classification of Disease  ­infectious diseases ­cancers ­immune disorders (research) ­genetic disorders ­mental disorders  ­trauma/injury  Infectious Diseases ­uncontrollable cell growth and proliferation  ­these cells do nothing but grow and divide ­space occupying lesions Tissue Level  ­causes of cancer  ­most cancers are caused by mutations through mistakes in replication or through environmental  factors called carcinogens  ­mutations may lead or turn on oncogenes which leads to uncontrolled cellular growth and  division Types of Cancer ­carcinomas originate in epithelial tissues  ­sarcomas originate in connective tissues or muscle ­lymphomas originate in lymphoid tissue ­leukemias originate in blood­forming tissues in the red blood marrow  Benign vs. Malignant  ­benign­ noncancerous tumors that occupy space, over­ruling healthy tissue  ­does not have the ability to spread, or metastasize  ­malignant­ cancerous, and have the ability to spread to other areas of the body, causing tissue  and organ damage  Genetic  ­includes mutations is genetic code  ­pressure of abnormal chromosomes  ­altered chromosomal structure  ­exposure to mutations, an agent capable of causing genetic mutation  Mental Disorder  ­conditions of the mind  ­disorders associated with behavioral and psychological well­being  Trauma/Injury  ­the results of trauma can lead to massive internal or external bleeding, shock or infection Epidemiology  ­the study of how diseases affect the overall health and well­being of a population  ­the spanish flu of 1918 killed over 50 million people  ­trends studied by epidemiologists helps spawn the birth of the many vaccines present today  ­heart disease/stroke and cancer account for more than 50% of all deaths per year  ­diabetes­leading cause kidney failure, amputations, and blindness every year ­arthritis­disables 19 million every year ­obesity­1 in 3 adults 


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