Cell Biology- Section 2, week 2 of notes
Cell Biology- Section 2, week 2 of notes 327
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This 2 page Class Notes was uploaded by Kali Webster on Tuesday February 23, 2016. The Class Notes belongs to 327 at Texas Christian University taught by in Spring 2016. Since its upload, it has received 18 views. For similar materials see Cell Biology in Biology at Texas Christian University.
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Date Created: 02/23/16
Cell biology- Chumley Lecture 2, week 2 - Secondary active transport: o Glucose and Na+ o SGLD1 protein utilizes secondary active transport o There is energy involved - Channels have a weaker bond to the solutes vs pumps - The energy to move ions against their electrochemical gradient can come directly from ATP and the electrochemical gradient - Neutrophils rolling inside the membrane of the capillary o Neutrophils use lectins to bind in the glycolylax membrane o Sugar residues are involved o ATP isn’t involved - Ca2+ getting in and out of the cell o PMCA: in the plasma membrane takes ATP to power it Takes Ca2+ out of the cell] o SERCA: in the membrane or SR or ER takes ATP to power it Takes Ca2+ and pumps it back into the SR or ER - Coupled transporters: o Uniport transports one solute, doesn’t couple the transport of one solute with another solute o Symport the two solutes move in one direction (they can use ATP) SGLT1 glucose and Na+ o Antiport the two solutes move in different directions (they can use ATP) Na+, K+ pump o THERE IS NEVER NOT AN ELECTROCHEMICAL GRADIENT o LOOK AT THE EXAMPLES OF TRANSMEMBRANE PUMPS - Channels: o Solute moves down its electrochemical gradient o K+ pump Vestibule K+ ions are surrounded by water Too big to go through the pore Water needs to be ripped off Selectivity filter filter that allows one some ions to go through Lined by carbonyl Oxygens (C=O: :O=C) Distance of oxygens are the selectivity filter - In the previous example of a K+ channel, Na+ can’t go through because… o Na+ is smaller than K+ and thus doesn’t interact with the selectivity filter tightly enough - Most channels are closed, and they all need some sort of signal to open - At the end of hair cells, there is a K+ channel at the end of the filaments o The hair cells vibrate on the tectorial membrane o The stereocilia on the hair cell goes one way, they open, goes the other way, they close o The liquid on the outside of the hair cells has a higher concentration than on the inside of the hair cells K+ rushes in - If there is no K+ outside of the hair cells… o Sensory cells release neurotransmitters (acetylcholine) o Ca2+ rushes in, and allows the vesicles to fuse and for the neurotransmitter to be released Sag Gets ramped up with K+ comes in
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