Lecture 7 PSYCH 254
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This 2 page Class Notes was uploaded by Brianna Nelson on Thursday February 25, 2016. The Class Notes belongs to PSYCH 254 at University of Wisconsin - Milwaukee taught by James Moyer in Spring 2016. Since its upload, it has received 41 views. For similar materials see Physiological Psychology in Psychlogy at University of Wisconsin - Milwaukee.
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Date Created: 02/25/16
Lecture 7 Types of Ion Channels Non-gated- always open Ligand-gated-binding of neurotransmitters opens channel Types of ligand-gated receptors: Iontropic-direct link to ion channel Metabotropic-indirect link to ion channel Voltage-Gated-depolarization of the membrane opens channel Ion-gated- increased concentration of ion opens channel Membrane recycling 1. Synaptic fusion 2. Pinocytosis of membrane 3. cisterna EPSP vs. IPSP Influx of Na+/Ca2+ EPSP Influx of Cl- or efflux of K+ IPSP Direct and indirect agonists/antagonists Direct – competitive Indirect –noncompetitive Drug Actions on Neurotransmission Agonists – activate the receptor Antagonists – blocks the receptor Ways in which drugs can affect synaptic transmission Packaging of the transmitter (loading vesicles) Synthesis of the transmitter Receiving the transmitter (postsynaptic receptors) Shipping the transmitter (vesicular release) Recycling/destroying the transmitter (reuptake)