week two Biology 230
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This 4 page Class Notes was uploaded by Alejandra Brito on Monday February 16, 2015. The Class Notes belongs to Biology 230 at San Francisco State University taught by kimberly Tanner in Spring2015. Since its upload, it has received 135 views. For similar materials see Biology 230 in Biology at San Francisco State University.
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Date Created: 02/16/15
Bio Notes Monday February 9 Key idea 0 Different cells have the same DNA but make different protein 0 Not every cell express Gena Protein Trait DNAbgeooo MRNA W Protein traits DNA gene 59 gt RNA Proteins Traits o Transcription in nucleus Big Idea 4 o The structure of DNA is key to its function 0 DNA replication DNA Transcription My RNA polymerase protein o Puts the pairs 0 Translation 0 MRNA happens in the ribome Codon 3L 0 Uses a set of 3 bases 0 Tr slation Going from 0 Nucleic acid amino acid 0 Pro ein 39 o RNAgt Protein At each stage of gene expression a new molecule Allele is a version of a gene Wednesday February 11 2015 Insertion and deletion position mutation always result in a frame shift Not all mutations involve just one nucleotide Mystery Gene Hemoglobin Gene 0 Sickle cell disease 0 Allele B Point mutation missense o Hemoglobin is responsible to carry oxygen to the body 0 Sickling changed of shape to res blood cell 0 Variety of physical Mutation Spontaneous Mutation Common 0 UV Ultraviolet radiation from sun 0 Xrays 0 Variety of chemicals Not always harmful Sickle cell mutation protects against malaria Loss of function 0 No longer does its job Gain of function 0 A new or different job Friday February 13 Biotechnology 0 Big idea is that about 15 of our DNA codes for protein 0 985 noncoding DNA 0 Promoters Central Dogma amp the spider Goats Goal produce spider silk in milk keep goat healthy Transgene gene from another organism is inserted at the 1 cell zygote stage of the goat so it s in every cell Promoter is a noncoding DNA sequence that controls when and where a genes is 39turn onquot transcribed Using bacteria to produce proteins to treat humans 0 Goal to make large amount of a human protein 0 The nonproteincoding introns in a human gene must be removed before bacteria can be used to produce the human protein PreRNA lntrons amp Exons o lntrons are cut out o Exons are expresses 0 mRNA Exons spliced together 0 this is how humans can make more proteins that they have genes We see DNA Biotechnology in o DNA ngerprinting Gene therapy Stems cells 0 Genetic modi ed food 0 Genetic testing 0 Etc Big ide Biotech and cancer are examples of central dogmagene expression in action
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