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Pharmacology PPT 301 Week 14 Notes

by: Lexie Stenson

Pharmacology PPT 301 Week 14 Notes PPT 301

Marketplace > University of North Dakota > Physiology > PPT 301 > Pharmacology PPT 301 Week 14 Notes
Lexie Stenson
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About this Document

Hello, these are notes taken from the study aids on Blackboard from chapters 40, 41, and 43.
Human physiology
James Haselton
Class Notes
PPT, 315, pharmacology, study, notes, color-coded, week, 14
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This 3 page Class Notes was uploaded by Lexie Stenson on Tuesday April 19, 2016. The Class Notes belongs to PPT 301 at University of North Dakota taught by James Haselton in Spring 2016. Since its upload, it has received 46 views. For similar materials see Human physiology in Physiology at University of North Dakota.


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Date Created: 04/19/16
Pharmacology  315  Week  14     Aluminum  Hydroxide   Trade  Name:  AlternaGEL   Therapeutic  Class:  Anti-­‐heartburn  agent   Therapeutic  Use:  Mostly  effective  used  in  combination  with  other  antiulcer  agents  for  the   symptomatic  relief  of  heartburn  due  to  PUD  or  GERD   Pharmacologic  Class:  Antacid   Mechanism  of  Action:  Neutralizes  stomach  acid  by  raising  pH  of  the  stomach  contents     Omeprazole   Trade  Name:  Prilosec   Therapeutic  Class:  Antiulcer  drug   Therapeutic  Use:  Short-­‐term  (4  to  8  week)  therapy  of  active  peptic  ulcers  and  GERD.  Used  for   longer  periods  in  patients  who  have  chronic  hypersecretion  of  gastric  acid,  a  condition  known   as  Zollinger-­‐Ellison  syndrome   Pharmacologic  Class:  Proton  pump  inhibitor   Mechanism  of  Action:  Reduced  acid  secretion  in  the  stomach  by  binding  irreversibly  to  the   enzyme  H+,  K+-­‐ATPase     Ranitidine   Trade  Name:  Zantac   Therapeutic  Class:  Antiulcer  drug   Therapeutic  Use:  Short  term  treatment  of  active  duodenal  or  benign  gastric  ulcers;  treatment   of  pathological  hypersecretory  conditions;  prophylaxis  of  stress-­‐induced  ulcers;  treatment  of   erosive  GERD;  relief  of  symptoms  of  heartburn  and  acid  indigestion   Pharmacologic  Class:  H2-­‐receptor  antagonist   Mechanism  of  Action:  Blocks  H2  receptors  in  the  stomach  to  decease  acid  production     Diphenoxylate/Atropine   Trade  Name:  Lomotil   Therapeutic  Class:  Antidiarrheal   Therapeutic  Use:  Effective  for  moderate  to  sever  diarrhea,  but  it  is  not  recommended  for   children   Pharmacologic  Class:  Opioid   Mechanism  of  Action:  Slows  peristalsis,  allowing  time  for  additional  water  reabsorption  from   the  colon  and  more  solid  stools     Pancrelipase   Trade  Name:  Cotazym   Therapeutic  Class:  Pancreatic  enzymes   Therapeutic  Use:  Replacement  therapy  for  patients  with  insufficient  pancreatic  exocrine   secretions,  including  those  with  pancreatitis  and  cystic  fibrosis   Pharmacologic  Class:  Digestive  enzymes   Mechanism  of  Action:  Disintegrates  into  trypsin,  amylase,  and  lipase,  which  break  down   proteins,  carbohydrates,  and  fats     Prochlorperazine   Trade  Name:  Compazine   Therapeutic  Class:  Antiemetic   Therapeutic  Use:  Treatment  of  severe  nausea  and  vomiting   Pharmacologic  Class:  Phenothiazine  antipsychotic   Mechanism  of  Action:  Blocks  dopamine  receptors  in  the  brain,  which  inhibits  signals  to  the   vomiting  center  in  the  medulla     Psyllium  Mucilloid   Trade  Name:  Metamucil   Therapeutic  Class:  Bulk-­‐type  laxative   Therapeutic  Use:  Preferred  drug  for  the  treatment  and  prevention  of  chronic  constipation,  and   may  be  taken  on  a  regular  basis  without  ill  effects.    Because  of  their  slow  onset  of  action,  they   are  not  used  when  a  rapid  and  complete  bowel  evacuation  is  necessary   Pharmacologic  Class:  Natural  product   Mechanism  of  Action:  An  insoluble  fiber  that  is  indigestible  and  not  absorbed  from  the  GI  tract.     When  taken  with  a  sufficient  quantity  of  water,  it  swells  and  increases  the  size  of  the  fecal   mass.    The  larger  the  size  of  the  fecal  mass,  the  more  the  defecation  reflex  will  be  stimulated,   thus  promoting  the  passage  of  stool     Sulfasalazine   Trade  Name:  Azulifidine   Therapeutic  Class:  Drug  for  inflammatory  bowel  disease   Therapeutic  Use:  Treatment  of  mild  to  moderate  symptoms  of  ulcerative  colitis;  used  off-­‐label   to  treat  Crohn’s  disease   Pharmacologic  Class:  5-­‐aminosalicylate,  sulfonamide   Mechanism  of  Action:  Inhibits  mediators  of  inflammation  in  the  colon  such  as  prostaglandins   and  leukotrienes     Desmopressin   Trade  Name:  DDAVP   Therapeutic  Class:  Antidiuretic  hormone  replacement   Therapeutic  Use:  Used  to  control  the  acute  symptoms  of  diabetes  insipidus  in  patients  who   have  insufficient  ADH  secretion   Pharmacologic  Class:  Vasopressin  analog   Mechanism  of  Action:  Acts  on  kidneys  to  increase  the  reabsorption  of  water     Hydrocortisone   Trade  Name:  Cortef   Therapeutic  Class:  Adrenal  hormone   Therapeutic  Use:  Treatment  of  adrenocortical  insufficiency     Pharmacologic  Class:  Corticosteroid   Mechanism  of  Action:  Inhibits  multiple  inflammatory  cytokines;  produces  multiple   glucocorticoid  and  mineralocorticoid  effects     Levothyroxine   Trade  Name:  Levothroid   Therapeutic  Class:  Thyroid  hormone   Therapeutic  Use:  Drug  of  choice  for  replacement  therapy  in  patients  with  low  thyroid  function   Pharmacologic  Class:  Thyroid  hormone  replacement   Mechanism  of  Action:  Increases  energy  metabolism,  producing  loss  of  weight,  improved   tolerance  to  environmental  temperature,  increased  activity,  and  increased  pulse  rate     Propylthiouracil   Trade  Name:  PTU   Therapeutic  Class:  Drug  for  hyperthyroidism   Therapeutic  Use:  Treatment  of  hyperthyroidism   Pharmacologic  Class:  Antithyroid  agent   Mechanism  of  Action:  Interferes  with  the  synthesis  of  T3  and  T4  in  the  thyroid  gland  and   prevents  the  conversion  of  T4  to  T3  in  the  target  tissues  


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