Pharmacology PPT 301 Week 14 Notes
Pharmacology PPT 301 Week 14 Notes PPT 301
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This 3 page Class Notes was uploaded by Lexie Stenson on Tuesday April 19, 2016. The Class Notes belongs to PPT 301 at University of North Dakota taught by James Haselton in Spring 2016. Since its upload, it has received 46 views. For similar materials see Human physiology in Physiology at University of North Dakota.
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Date Created: 04/19/16
Pharmacology 315 Week 14 Aluminum Hydroxide Trade Name: AlternaGEL Therapeutic Class: Anti-‐heartburn agent Therapeutic Use: Mostly effective used in combination with other antiulcer agents for the symptomatic relief of heartburn due to PUD or GERD Pharmacologic Class: Antacid Mechanism of Action: Neutralizes stomach acid by raising pH of the stomach contents Omeprazole Trade Name: Prilosec Therapeutic Class: Antiulcer drug Therapeutic Use: Short-‐term (4 to 8 week) therapy of active peptic ulcers and GERD. Used for longer periods in patients who have chronic hypersecretion of gastric acid, a condition known as Zollinger-‐Ellison syndrome Pharmacologic Class: Proton pump inhibitor Mechanism of Action: Reduced acid secretion in the stomach by binding irreversibly to the enzyme H+, K+-‐ATPase Ranitidine Trade Name: Zantac Therapeutic Class: Antiulcer drug Therapeutic Use: Short term treatment of active duodenal or benign gastric ulcers; treatment of pathological hypersecretory conditions; prophylaxis of stress-‐induced ulcers; treatment of erosive GERD; relief of symptoms of heartburn and acid indigestion Pharmacologic Class: H2-‐receptor antagonist Mechanism of Action: Blocks H2 receptors in the stomach to decease acid production Diphenoxylate/Atropine Trade Name: Lomotil Therapeutic Class: Antidiarrheal Therapeutic Use: Effective for moderate to sever diarrhea, but it is not recommended for children Pharmacologic Class: Opioid Mechanism of Action: Slows peristalsis, allowing time for additional water reabsorption from the colon and more solid stools Pancrelipase Trade Name: Cotazym Therapeutic Class: Pancreatic enzymes Therapeutic Use: Replacement therapy for patients with insufficient pancreatic exocrine secretions, including those with pancreatitis and cystic fibrosis Pharmacologic Class: Digestive enzymes Mechanism of Action: Disintegrates into trypsin, amylase, and lipase, which break down proteins, carbohydrates, and fats Prochlorperazine Trade Name: Compazine Therapeutic Class: Antiemetic Therapeutic Use: Treatment of severe nausea and vomiting Pharmacologic Class: Phenothiazine antipsychotic Mechanism of Action: Blocks dopamine receptors in the brain, which inhibits signals to the vomiting center in the medulla Psyllium Mucilloid Trade Name: Metamucil Therapeutic Class: Bulk-‐type laxative Therapeutic Use: Preferred drug for the treatment and prevention of chronic constipation, and may be taken on a regular basis without ill effects. Because of their slow onset of action, they are not used when a rapid and complete bowel evacuation is necessary Pharmacologic Class: Natural product Mechanism of Action: An insoluble fiber that is indigestible and not absorbed from the GI tract. When taken with a sufficient quantity of water, it swells and increases the size of the fecal mass. The larger the size of the fecal mass, the more the defecation reflex will be stimulated, thus promoting the passage of stool Sulfasalazine Trade Name: Azulifidine Therapeutic Class: Drug for inflammatory bowel disease Therapeutic Use: Treatment of mild to moderate symptoms of ulcerative colitis; used off-‐label to treat Crohn’s disease Pharmacologic Class: 5-‐aminosalicylate, sulfonamide Mechanism of Action: Inhibits mediators of inflammation in the colon such as prostaglandins and leukotrienes Desmopressin Trade Name: DDAVP Therapeutic Class: Antidiuretic hormone replacement Therapeutic Use: Used to control the acute symptoms of diabetes insipidus in patients who have insufficient ADH secretion Pharmacologic Class: Vasopressin analog Mechanism of Action: Acts on kidneys to increase the reabsorption of water Hydrocortisone Trade Name: Cortef Therapeutic Class: Adrenal hormone Therapeutic Use: Treatment of adrenocortical insufficiency Pharmacologic Class: Corticosteroid Mechanism of Action: Inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects Levothyroxine Trade Name: Levothroid Therapeutic Class: Thyroid hormone Therapeutic Use: Drug of choice for replacement therapy in patients with low thyroid function Pharmacologic Class: Thyroid hormone replacement Mechanism of Action: Increases energy metabolism, producing loss of weight, improved tolerance to environmental temperature, increased activity, and increased pulse rate Propylthiouracil Trade Name: PTU Therapeutic Class: Drug for hyperthyroidism Therapeutic Use: Treatment of hyperthyroidism Pharmacologic Class: Antithyroid agent Mechanism of Action: Interferes with the synthesis of T3 and T4 in the thyroid gland and prevents the conversion of T4 to T3 in the target tissues
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