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Bio 115, Week 1, Lecture 1

by: gtan51097

Bio 115, Week 1, Lecture 1 01:119:115

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About this Document

First day of notes taken on 9/7/2016. Notes will follow the Monday/Wednesday lectures in ARC 103 with Dr. Beal (I know it says Dr. Transue but you know, WebReg lol).
General Biology I
Dr. Gregory Transue
Class Notes
Biology, learning, long-term, Potentiation, short-term, memory, neural, Plasticity




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This 2 page Class Notes was uploaded by gtan51097 on Thursday August 11, 2016. The Class Notes belongs to 01:119:115 at Rutgers University taught by Dr. Gregory Transue in Fall 2016. Since its upload, it has received 29 views. For similar materials see General Biology I in Biological Sciences at Rutgers University.

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Date Created: 08/11/16
9/7/2016 Lecture 1: Biology and Learning I. Memory and Learning  Nervous System (NS) = neurons and supporting cells  Requires repeated long-term interactions between these cells  Memory is storage  LT vs. ST and LTP  Learning is using that info appropriately A. Long-Term Potentiation (LTP)  Increase in synaptic strength  memory formation  Is activity-dependent: be active and use info o Recall, practice, teaching, embarrassment  Use of info is a sorting process o Important (used) info is kept o Unimportant info will be discarded  LTP: Molecular Complexity 1) As synapse becomes active, chem signals sent from one neuron to the next 2) As activity increases at a synapse, receiving neuron upregulates. It activates more proteins that can receive that signal. 3) Receiver proteins persist for up to several weeks  Facilitated by organizing  “Chunking”: learning sets of related info  Study in segments  Review every few weeks  Determine what you really know: VERIFY  Try to explain to someone else B. Neuronal Development  Basic structure of brain determined by genetics as an embryo (embryonic)  Involves 1) Gene expression: How DNA is used 2) Signal transduction when expression occurs  Genetics  Occur at chem synapses and dependent on neuronal plasticity and activity C. LT vs ST  ST: released if not used  LT/working memory: activated when info needs to be retained; pulled into ST and used D. Neuronal Plasticity = NS modified after birth  Brain can be remodeled by experiences  Changes are activity dependent  Activity at synapses tell the brain what is important  Use it or lose it  Synapse o Lots of activity  many connections o Lack of activity  lose connections  If multiple synapses active, strengthens response at all synapses


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