Bio 115, Week 1, Lecture 1
Bio 115, Week 1, Lecture 1 01:119:115
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This 2 page Class Notes was uploaded by gtan51097 on Thursday August 11, 2016. The Class Notes belongs to 01:119:115 at Rutgers University taught by Dr. Gregory Transue in Fall 2016. Since its upload, it has received 29 views. For similar materials see General Biology I in Biological Sciences at Rutgers University.
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Date Created: 08/11/16
9/7/2016 Lecture 1: Biology and Learning I. Memory and Learning Nervous System (NS) = neurons and supporting cells Requires repeated long-term interactions between these cells Memory is storage LT vs. ST and LTP Learning is using that info appropriately A. Long-Term Potentiation (LTP) Increase in synaptic strength memory formation Is activity-dependent: be active and use info o Recall, practice, teaching, embarrassment Use of info is a sorting process o Important (used) info is kept o Unimportant info will be discarded LTP: Molecular Complexity 1) As synapse becomes active, chem signals sent from one neuron to the next 2) As activity increases at a synapse, receiving neuron upregulates. It activates more proteins that can receive that signal. 3) Receiver proteins persist for up to several weeks Facilitated by organizing “Chunking”: learning sets of related info Study in segments Review every few weeks Determine what you really know: VERIFY Try to explain to someone else B. Neuronal Development Basic structure of brain determined by genetics as an embryo (embryonic) Involves 1) Gene expression: How DNA is used 2) Signal transduction when expression occurs Genetics Occur at chem synapses and dependent on neuronal plasticity and activity C. LT vs ST ST: released if not used LT/working memory: activated when info needs to be retained; pulled into ST and used D. Neuronal Plasticity = NS modified after birth Brain can be remodeled by experiences Changes are activity dependent Activity at synapses tell the brain what is important Use it or lose it Synapse o Lots of activity many connections o Lack of activity lose connections If multiple synapses active, strengthens response at all synapses