BISC 336 Week 1 Day 1
BISC 336 Week 1 Day 1 Bisc 336, Section 5
Popular in Genetics
Popular in Department
verified elite notetaker
This 3 page Class Notes was uploaded by Madlyn Notetaker on Monday August 22, 2016. The Class Notes belongs to Bisc 336, Section 5 at University of Mississippi taught by Dr. Erik Hom in Fall 2016. Since its upload, it has received 7 views.
Reviews for BISC 336 Week 1 Day 1
Report this Material
What is Karma?
Karma is the currency of StudySoup.
You can buy or earn more Karma at anytime and redeem it for class notes, study guides, flashcards, and more!
Date Created: 08/22/16
Genetics Hom section 5 Day 18/22/16 Notes Everything in black is notes from class Everything in red is what I added when I read the chapter Ch. 1Intro to Genetics What is genetics? o It is a branch of biology devoted to the study of heredity/ variation… of traits (charaterstics) Variation we all look different Characteristics observed through phenotypes Basis of traits? o Genes 2 definitions of genes 1. Fundamental unit of heredity information 2. Physically encoded by a locus (region) of DNA o contains info that is passed down o heredity DNA, sex, evolution Sex is used to get recombination which creates variation o Variation Statistics (population) If you want the odds of you getting a trait or disease it needs to be # of people that have it over the population o Ex. Sickle cell 1/400 Africans have it o Phenotypes Generally, a behavior (environment) Observable features o Genotype Set of alleles for a given trait carried by the organism Can also be a physical trait like red hair o Central Dogma Means fundamental This was a worksheet in class It examines the molecular level Explains how genes affect phenotype Describes the flow of genetic information on biology systems via polymers DNA, RNA, Proteins o DNA structure was discovered by Watson Crick Can go through replication Methylation (CH3) groups can affect the epigenetics and modify genes Ex. Obesity o Short/Long RNA affects/modifies transcription o Made of four nucleotide bases Adenine, guanine, thymine, cytosine o AT and CG o RNA is single stranded and has Urine instead of thymine Prions An infectious agent that is mad entirely of proteins Leads to a disease similar to a viral infection such as mad cow disease Inteins Also known as introns in protein splicing Can be removed or added to an extien Transcription The process in which DNA is unwound and transcribed into RNA o This takes place in the nucleus o Creates a commentary RNA sequence o RNA then moves to the cytoplasm it attaches to the ribosomes called mRNA mRNA can be synthesized into a protein through translation translated in triplet couples called codons these codons code for different proteins translation takes place on the ribosome tRNA is used to help assemble proteins Reverse Transcription The process of going from RNA to DNA HIV does this o Proteins Made from 20 different amino acids Need to memorize structure and properties Enzymes are the largest category of proteins Other proteins are hemoglobin, insulin, collagen Modifications that could be made to the central dogma in the past 50 years o Reverse transcription HIV goes from RNA to DNA and encodes itself into the genome of the host Rous Sarcoma Virus (RSV) the 1 cancer virus found o RNA Replication RNA can also replicate itself like DNA and the copies can chill for a while and not get translated like DNA can make copies and not be transcribed Mutation o Can modify or eliminate the function of that protein This can alter the phenotype Ex. Sickle cell Sickle Cell Anemia o SINGLE PONT MUTATION – on the codon 6 Glutamic acid to valine GAG to GUG Individuals with two betaglobin genes have sickle cell 1/400 in African community is affected get goopy blood. b/c it is hydrophobic amino acid the cells begin to aggregate in the cell chromosome 11 mutation
Are you sure you want to buy this material for
You're already Subscribed!
Looks like you've already subscribed to StudySoup, you won't need to purchase another subscription to get this material. To access this material simply click 'View Full Document'