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Biochem, week 1

by: Adam Reinstein

Biochem, week 1 BCH 3033

Adam Reinstein
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About this Document

This covers Dr.Hace's first powerpoint and has some added notes from the textbook
Biochemistry 1
Dr. Haces
Class Notes
biochemistry, Chemistry, Organic Chemistry, Science, Biology




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This 3 page Class Notes was uploaded by Adam Reinstein on Friday September 2, 2016. The Class Notes belongs to BCH 3033 at Florida Atlantic University taught by Dr. Haces in Fall 2016. Since its upload, it has received 13 views. For similar materials see Biochemistry 1 in Biochemistry at Florida Atlantic University.


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Date Created: 09/02/16
Biochemistry Notes Chapter 1: Chemistry Is the Logic of Biological Phenomena I. Distinctive Properties of Living Systems A) Organisms are complicated and highly organized B) Biological structures serve functional purposes C) Living systems are actively engaged in energy transformations. D) Living systems have a remarkable capacity for self-replication II. Biomolecules A) H, O, C, and N form covalent bonds by electron- pair sharing B) All biomolecules contain carbon C) Different bonds have different energies associated with them (look at the chart) i. With these known bond energies we can determine if a chemical reaction will proceed or not III. Example problem: CH4 + 2O2  =  CO2  + 2H2O III. What type of reaction is this? III. III. Break 4 C­H bonds =        4 x 414 KJ III. III. III. Break 2 O = O bonds =     2 x 402 KJ III. III.Properties of Form 2 x C = O bonds = ­ 2 x 686 KJ Biomolecules Reflect Their Form 4 O­H bonds  =      ­ 4 x 460 KJ Fitness to the Living Total      = ­ 752 KJ/react. Condition Since the net energy change is negative, this is a endothermic reaction A) Macromolecules and Their Building Blocks Have a “Sense” or Directionality i. These molecules are not symmetrical, and have a “head” and a “tail.” ii. Because of this macromolecules can be sequenced and used to convey information (Phe-Aly-Leu is different from Leu-Phe-Aly) B) Biomolecules have Characteristic Three-Dimensional architecture C) Weak Forces Maintain Biological Structure i. Weak forces impart stability to the structures ii. Because these forces are weak and essential to life they impart a Narrow Range for Life Conditions. They are active only within a narrow range of environmental conditions, such as temperature, ionic strength, and relative acidity. D) Virtually every metabolic reaction is catalyzed by an enzyme IV. Intermolecular Forces A) Strong forces: i. Ion- Ion in solid or gas phase. ii. Ion-dipole (water – ions) B) All the following are weak forces: i. Ion- Ion in water ii. Hydrogen bonds- form from a hydrogen atom covalently bonded to an electronegative atom (such as O or N) and a second electronegative atom that serves as the hydrogen bond acceptor. iii. Van der Waals forces- induced electrical interactions between closely approaching atoms iv. Ionic interactions- attractive forces between oppositely charged structures v. Hydrophobic interactions- occur due to the tendency of water to exclude nonpolar group C) Hydrogen bonds i. X-H where x must be very electro negative in donors(OH, NH in biomolecules) ii. Directional- This is easily observed in Ice which aligns H atoms on a direct line between the two O atoms. iii. Not a true bond, but strongest of all non-covalent interactions iv. Amphoteric- can react with acids and bases


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