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BIOS Week 3 Class Notes

by: Samantha Ragland

BIOS Week 3 Class Notes BIOS 1300

Marketplace > Ohio University > Biological Sciences > BIOS 1300 > BIOS Week 3 Class Notes
Samantha Ragland

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About this Document

Goes over what we went over during week 3
Human Anatomy and Physiology
Dr. Foster
Class Notes
25 ?




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This 3 page Class Notes was uploaded by Samantha Ragland on Sunday September 11, 2016. The Class Notes belongs to BIOS 1300 at Ohio University taught by Dr. Foster in Fall 2016. Since its upload, it has received 7 views. For similar materials see Human Anatomy and Physiology in Biological Sciences at Ohio University.


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Date Created: 09/11/16
BIOS1300 Week3  Lipidcomponents o Phospholipids  RelativelyimpermeabletomostH2O solublemolecules andallowsfluidity o Cholesterol  Strengthensto plasmamembranebymakingit less deformable  Stabilizesplasmamembraneatextremetemperatures  Embeddedbetweenthephospholipids o Glycolipids  Located at theouterlayer  Glycolipid+Glycoprotein=Glycocalyxwhichis uniqueto each person  Patternofsugars is uniquetoeach person  Carbohydraterichzoneoncell surface  Helps preventundesirableproteininteractions  Helps protectthe cell o FunctionsofLipidsinPlasma Membrane  Does notdissolvewhen comes in contactwith H2O  Effectivenonpolarbarriertomostsubstances  Smalland nonpolarsubstancescanmovethroughthis barrierwithoutassistance  Smalland nonpolarsubstancescanmovethroughthis barrierwithoutassistance  Membraneproteinsperformveryspecificfunctions o Make up 2-10% ofplasmamembranebutaccount for 50% of weight in anaverage cell o There are 2structuraltypes  Integralmembraneproteins  Embeddedwithinplasmamembrane  Amphipathic o Some are “trans membrane”  Extendfrom endto end o Some are partiallyembedded  Peripheralmembraneproteins  Attachedtothe insideor outsideofthe surface of the membrane  Couldbeattachedto theintegralproteinby noncovalentbondsremovedwithoutdisrupting membraneintegrity o Functionsofdifferentmembraneproteins  Receptors  Bindspecificmoleculesat cell surface  Ligands-moleculesreleasedformthe cell thatbind to receptorswithinthe plasmamembraneof anothercell o ExamplesNTM(neurotransmitters)and hormones  Transportproteins 2  Regulatemovementof substancesacrossa plasma membrane o Channels,carriers,and pumps  Identitymarkers  Proteinsor glycoproteinscommunicatetoothercells thattheybelongto thebody o Nonselfvs.self  Enzymes  Catalyzingchemicalreactions o Some enzymes adhereto thecell surface  Cell-adhesionproteins  Cell-to-cellattachment o Bindone cell toanotheror bindcytoskeleton to bilayer  ProtonPump inhibitor(PPI)Prilosec(omeprazole) 1. Prilosecgets absorbedinthe bloodthroughthesmall intestine 2. Drug is nonpolarandcrossesplasmamembrane 3. Becomes protonatedincytoplasmofparietalcellof stomach 4. Prilosecchanges shapesoit fits andinhibitstheH+/K+ = ATPase pump 5. Blocks ATPso pumpcannotmoveH+ intostomachlumen 6. Over severaldays thereis a 99% reductioninacid production 3


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