Actions of a Ligand
Actions of a Ligand PSYC 1000
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This 1 page Class Notes was uploaded by Cydney Tinsley on Tuesday September 20, 2016. The Class Notes belongs to PSYC 1000 at University of Colorado Denver taught by Alex Northcutt in Fall 2016. Since its upload, it has received 25 views. For similar materials see Introduction to Psychology in Psychology (PSYC) at University of Colorado Denver.
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Date Created: 09/20/16
Cydney Tinsley Psychology Week 5: Actions of the Ligand Actions of the Ligand 1. The Limbic System a. Phineas Gage i. Involved in an accident where a pike went through his chin and up out through his brain. Amazingly, he survived. ii. They believed he severed his pre-frontal cortex, which has to do with impulse control, as he completely changed temperaments. 2. Neuro-transmitters and Receptors cannot be described except for: a. GABA b. Glutamate 3. GABA is inhibitory, meaning it inhibits the actions of a neuron. 4. Glutamate is excitatory, meaning it excites and activates neurons to fire an action potential. 5. Acetylcholine: The chemical responsible for learning, memory, motor- functioning and sleep-wake cycles. 6. Dopamine: The chemical responsible for reward/pleasure, compulsion, motor- functioning, and mood. 7. Serotonin: The chemical responsible for mood, memory, appetite, and cognition. 8. Actions of the Ligand a. Agonist: Activates signaling and receptors. Can be endogenous or exogenous. b. Antagonist: Binds to the same spot that an agonist would but blocks it so that a future agonist cannot use it. Antagonists do not activate receptors. c. Exogenous: Something created from the outside of the body, (i.e., drugs). d. Endogenous: Something made inside the body. e. Mesolimbic Dopamine Pathway: Sends dopamine signaling from VTA to Prefrontal Cortex. Promotes behavior beneficial for survival, (i.e., eating, sleeping, sex, etc.)
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