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This 1 page Class Notes was uploaded by gtan51097 on Thursday September 22, 2016. The Class Notes belongs to 01:830:364 at Rutgers University taught by Dr. Arthur Tomie in Fall 2016. Since its upload, it has received 3 views.
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Date Created: 09/22/16
9/20/2016 Lecture 3: The Scientific Short Story “The Tail of the Raccoon: Secrets of Addiction” “Tail of the Raccoon: Secrets of Addiction” Developed to educate the general public about the science of the origins of the loss of self-control Storyline modeled on the Misbehavior Effect described by the Brelands Lesson is that pairings of object w/ reward induce disconnect between action and intention Features Common to Sign-Tracking and Drug-Taking Acquired: both responses are acquired as a function of experience w/ pairings of stimulus (CS) with a reward (US) Reflexive: both exhibit properties of an acquired reflex, performed automatically w/out forming intention to do so Triggered: both responses triggered or elicited by a CS that has been repeatedly paired w/ drug reward US Involuntary: both responses difficult to restrain, control, or suppress Compulsive: both responses are performed even though intending not to; subject compelled to act despite intention Durable: once responding has developed, little evidence that it can be eradicated Relapse-like effects spontaneous recovery, reacquisition savings, long-term retention The Disconnect: Action vs. Intention S-T CR performance occurs even when it serves no purpose other than to cancel reward Negative automaintenance effect: Food (US) omitted if subject contacts the lever (CS). Despite contingent non-reinforcement, subjects contact the lever and lose the majority of the food. The Long-Box Experiment: Light (CS) is illuminated for 5 sec followed by raising of food (US) hopper for 5 sec. Light is gradually moved further way from food hopper. S-T CR performance directed at light serves no purpose other than to reduce time available to eat food Cocaine cue lights during infusion of cocaine. Rats approach and contact light cue. Extinction of cocaine self-administration. Rats run across electrified grid floor and succumb to shock in order to continue interacting w/ light.
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