Endocrinology - Exam 1 (Answers)
Endocrinology - Exam 1 (Answers) BIOL 4110
Popular in Endocrinology
verified elite notetaker
Popular in Biology
This 4 page Class Notes was uploaded by Michelle Notetaker on Thursday September 22, 2016. The Class Notes belongs to BIOL 4110 at University of North Texas taught by Dr. Harris D Schwark in Fall 2016. Since its upload, it has received 12 views. For similar materials see Endocrinology in Biology at University of North Texas.
Reviews for Endocrinology - Exam 1 (Answers)
Report this Material
What is Karma?
Karma is the currency of StudySoup.
Date Created: 09/22/16
Endocrinology Exam 1 (Answers) 1) Which class of hormones is synthesized from tyrosine? C. catecholamines 2) What type of receptor is the secretin receptor? A. G proteincoupled receptor 3) Which receptor can be found in the cytoplasm in the absence of hormone? D. glucocorticoid receptor 4) The insulin receptor is an example of a B. receptor tyrosine kinase 5) Intracellular receptors D. (b)&(c) are correct (b) may be located within target cell nuclei. (c) may dissociate from chaperone proteins following ligand binding. 6) ____ binds to alpha subunits of G proteins when they are activated following hormone binding. G. GTP 7) Which receptors are bound to Hormone Response Elements, even in the absence of hormone? B. steroid hormone receptors 8) The transcription factors called STATs are activated by which class of receptor? D. cytokine receptor 9) PKA (Protein kinase A) A. GPCR ⍺ₛ 10)PKC (Protein kinase C) B. GPCR ⍺ᵨ(<--this is a q) 11)DAG(diacylglycerol) B. GPCR ⍺ᵨ 12)MAPK (Mitogenactivated protein kinase) D. Receptor serinethreonine kinase 13)RAP (Receptorassociated protein) C. Receptor tyrosine kinase 14)IP3 (inositol 1,4,5triphosphate) B. GPCR ⍺ᵨ 15)PKB(Akt) D. receptor serinethreonine kinase 16)SMAD D. receptor serinethreonine kinase 17)(T/F) Steroid hormones are stored in smooth endoplasmic reticulum. False 18)An ultradian rhythm is a C. rhythm with a period of much less than a day. 19)Which of the following does not act directly on gastric parietal cells to affect HCl secretion? E. (c) and (d) are correct. (c) somatostatin (d) cholecystokinin 20)Which of the following inhibits gastrin release? D. enterogastrones from small intestine 21)(T/F) Gastrin stimulates ECL cells through a local paracrine action. False 22)Which receptor mediates most of gastrin’s effects? B. CCK2 receptor 23)The presence of food in the stomach affects the release of D. gastrin 24)Activation of stomach mechanoreceptors by distension plays a role in which phase of gastric function? B. gastric phase 25)Secretin and CCK are released primarily during the C. intestinal phase 26)The migrating myoelectric complex (MMC) seems to be related to secretion of D. motilin 27)Which hormone has enterotropic effects on the intestines? D. GLP2 28)Motilin levels are highest C. during the interdigestive period. 29)Before the signal peptide is removed, a hormone is called either a Prohormone or a Preprohormone 30)Gastric mechanoreceptor activation initiates a vagovagal reflex that results in the release of ____ which acts on enteric neurons. Acetylcholine (ACH) 31)What is the ligand for proteinaseactivated receptor? Pepsin 32)How do protein hormones differ from steroid hormones in terms of their storage within an endocrine cell? Protein hormones are stored in secretory vesicles, while steroid hormones are stored in the follicle associated with synthesis. 33)How does binding to serum transport proteins influence hormone metabolism and hormone action? Ensures that a constant supply of the hormone goes to the cells and tissues and not lost through urine. 34)Define incretin. Liste two incretins. Group of metabolic hormones that stimulate a decrease in blood glucose levels. GLP1 and GIP 35)What is the relationship between GLP1 and Glucagon? GLP1 inhibits glucagon secretion and gastric emptying. 36)Compare and contrast Secretin and CCK in the duodenum. Include stimulus for secretion, origin, target, and physiological effect on target cells. ● Secretin: Stimulus acidification of the duodenum (small intestine) Origin bile ducts in gallbladder Targets/Effects (Pancreas) stimulates secretion of alkaline buffers to neutralize intestinal pH. (Stomach) inhibits gastric secretion and motility. (Liver) increases rate of bile secretion. ● CCK: Stimulus chyme of undigested lipids/proteins entering the intestine. Origin duodenum (mucosal epithelium) Targets/Effects (Pancreas) production of pancreatic enzymes. (Gallbladder) contraction of gallbladder. (Duodenum) relaxation of hepatopancreatic sphincter. (Stomach) inhibits gastric secretion and motility. (CNS) may reduce hunger.