Sept 29 Notes: Dr. Dakhil Presentation
Sept 29 Notes: Dr. Dakhil Presentation HP 330
Popular in Cancer: Perspectives and Controversies
Popular in Health Professions
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This 2 page Class Notes was uploaded by Sydney Brummett on Thursday September 29, 2016. The Class Notes belongs to HP 330 at Wichita State University taught by Dr. Paul Danner in Fall 2016. Since its upload, it has received 50 views. For similar materials see Cancer: Perspectives and Controversies in Health Professions at Wichita State University.
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Date Created: 09/29/16
Dr. Dakhil Presentation Notes • From Cancer Center of Kansas • Covered the basic concepts of medical oncology • What is cancer? o Cancer cells divide constantly o Only takes “one bad division” of cells for cancer to begin § Abnormality in genome of the particular cell causes cancer § Regulator genes allow cells to reproduce in orderly fashion (but not in cancer cells) • How do we diagnose cancer? o 1 cm tumor is one billion cancer cells § This is the size a tumor needs to be to be visible on a scan, or to be felt § Earliest size that a tumor can be found o Fast growing tumors can double in size in a month o Physical examinations are very important o CT Scan o MRI Scan § Magnetic (Not x-ray) § Good for organs that don’t move (e.g. bones, brain, not lungs) o PET Scan § Does not tell you size, but tells you activity § Sugar is taken in and the cancer cells, because they’re rapidly dividing, taken in the sugar and it shows up on the scan o Biopsy § Needle (Negative results may not be accurate, because the needle could have missed the cancer cells) § Excisional • How to combat cancer? o Wherever a cancer cell goes, it still looks like it’s parent § Why cancers are identified by sight of origin o Weapons we have: § Surgery § Radiation • Like a blow-torch • Side-effects are localized to where you radiate • Cyber knife (very precise form of radiation) § Chemotherapy • Drugs that disrupt DNA from forming • A poison • Faster a tumor grows the more chemotherapy works • Makes you loose your hair (because hair cells are fast growing) • Nausea, vomiting, and diarrhea are common side effects • Some specific chemotherapies have other specific side effects § Targeted therapy • Anti-hormone pills that block the gene from working • Medical oncology is going more towards this therapy § You can combine the chemotherapy and other weapons in order ot kill the cancer o Formula of happiness (for life, not just cancer) § Achievement/expectation > 1 • Set up achievable expectations § Benefit/side effects > 1 • Maximum Tolerated Dose (MTD) o Phase 1 (find MTD) o Phase 2 (finding a cancer to test it on) o Phase 3 (comparing the new drug to the old drug) o Phase 4 (researching side effects that may have been missed) • Many researchers wonder why ne need to use MTD § Hope and expectation • Expectation is scientific • Hope is more religious o We have no right to disrupt hope
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