New User Special Price Expires in

Let's log you in.

Sign in with Facebook


Don't have a StudySoup account? Create one here!


Create a StudySoup account

Be part of our community, it's free to join!

Sign up with Facebook


Create your account
By creating an account you agree to StudySoup's terms and conditions and privacy policy

Already have a StudySoup account? Login here

Synthetic Cannabinoids

by: Chelsey Smith

Synthetic Cannabinoids FSC 440

Chelsey Smith
GPA 3.9

Preview These Notes for FREE

Get a free preview of these Notes, just enter your email below.

Unlock Preview
Unlock Preview

Preview these materials now for free

Why put in your email? Get access to more of this material and other relevant free materials for your school

View Preview

About this Document

These notes cover synthetic cannabinoids, their prevalence around the world, pharmacokinetics, pharmacodynamics, adverse effects, and distribution.
Drug Identification
Class Notes
Forensic, Science, durg, cannabinoid, Chemistry
25 ?




Popular in Drug Identification

Popular in Forensic Science

This 4 page Class Notes was uploaded by Chelsey Smith on Thursday September 29, 2016. The Class Notes belongs to FSC 440 at University of Southern Mississippi taught by Nesser in Fall 2016. Since its upload, it has received 12 views. For similar materials see Drug Identification in Forensic Science at University of Southern Mississippi.

Similar to FSC 440 at USM

Popular in Forensic Science


Reviews for Synthetic Cannabinoids


Report this Material


What is Karma?


Karma is the currency of StudySoup.

You can buy or earn more Karma at anytime and redeem it for class notes, study guides, flashcards, and more!

Date Created: 09/29/16
FSC 440- Drug Identification September 28, 2016 Synthetic Drug Abuse Synthetic Cannabinoids (28%) Synthetic Cathinones (25%) Most severely abused synthetic drug categories CSA Schedule I Synthetic Cannabinoids  Manmade chemical compounds which have psychoactive effects- to mimic/enhance psychoactive drugs Street Names: designer drugs, synthetic marijuana, new psychoactive substance (NPS), spice, K2, lave, aroma, wicked x Prevalence  Became popular among younger people- sold as an herbal incense, jewelry cleaner, or plant food and is labeled “not for human consumption”  Cost: $30-40 per 3 grams  Available online and in gas stations  The calls to poison control has dramatically increased for synthetic cannabinoids  The drug is mixed with and or dissolved into a liquid and then sprayed onto dried plant materials to form “synthetic marijuana”  This mixture is then smoked, vaped, snorted, ingested History  Initially developed as a part of research efforts to make new medicines- Roger Adams 1940s  In the 80s and 90s a series of synthetic cannabinoids were made (JWH-018)  First appeared in Europe in 2004 and US in 2008  Banned in Germany 2009  5 synthetic cannabinoids were placed on emergency CI in 2011  As of 2013 there are over 400 different synthetic cannabinoids that have been identified Mechanisms  A Cannabinoid receptor in the CNS was identified in 1988  Receptors occur in many areas of the brain  CB1- found mainly in CNS  CB2- found in the immune system and tissues  Affinity to bind to receptors CB1 > THC CB1 > CB2  Why do humans have receptors made for plants? o There must be an endogenous neurotransmitter-like substance that acts on the receptors o Several of these have now been discovered- the endocannabinoids  Two main endocannabinoids have been found: AEA and 2-AG o They are retrograde messengers that carry information in the opposite direction from postsynaptic to presynaptic Psychoactive Effects  Euphoria  Sociability  Anxiolytic  Relaxant  Stimulant Severe Side Effects  Increased heart rate and blood pressure  Anxiety  Paranoia  Headache  Vomiting psychosis  Seizures  Diaphoresis Pharmacokinetics  Serum concentration of JWH-018 decreases rapidly over several hours  It is quickly metabolized  After 6 hours an analyst can only give qualitative answers indicating if the drug is present in a person’s system and cannot measure how much is in the body Pharmacodynamics  Blood concentrations below 1 ng/ml within an hour or two after smoking  Detectable in oral fluids  Urine concentrations may be detectable for 24 hours  It is hard to identify synthetic cannabinoids because there are many metabolites of the drug Forensic Analysis  Complexity of drug  Relatively fast excretion  Various metabolites  Vast number of new drugs v limited research  Lack of availability of reference standards  There is not one immunoassay test to identify the drug  Screening and Confirmatory tests include: GC-MS/MS or LC-MS/MS Summary- this list of questions covers the main topics from this lecture What are synthetic drugs? Why do emerging synthetic drugs circumvent drug laws? Why is it different for forensic scientists to identify synthetic cannabinoids?


Buy Material

Are you sure you want to buy this material for

25 Karma

Buy Material

BOOM! Enjoy Your Free Notes!

We've added these Notes to your profile, click here to view them now.


You're already Subscribed!

Looks like you've already subscribed to StudySoup, you won't need to purchase another subscription to get this material. To access this material simply click 'View Full Document'

Why people love StudySoup

Jim McGreen Ohio University

"Knowing I can count on the Elite Notetaker in my class allows me to focus on what the professor is saying instead of just scribbling notes the whole time and falling behind."

Anthony Lee UC Santa Barbara

"I bought an awesome study guide, which helped me get an A in my Math 34B class this quarter!"

Bentley McCaw University of Florida

"I was shooting for a perfect 4.0 GPA this semester. Having StudySoup as a study aid was critical to helping me achieve my goal...and I nailed it!"


"Their 'Elite Notetakers' are making over $1,200/month in sales by creating high quality content that helps their classmates in a time of need."

Become an Elite Notetaker and start selling your notes online!

Refund Policy


All subscriptions to StudySoup are paid in full at the time of subscribing. To change your credit card information or to cancel your subscription, go to "Edit Settings". All credit card information will be available there. If you should decide to cancel your subscription, it will continue to be valid until the next payment period, as all payments for the current period were made in advance. For special circumstances, please email


StudySoup has more than 1 million course-specific study resources to help students study smarter. If you’re having trouble finding what you’re looking for, our customer support team can help you find what you need! Feel free to contact them here:

Recurring Subscriptions: If you have canceled your recurring subscription on the day of renewal and have not downloaded any documents, you may request a refund by submitting an email to

Satisfaction Guarantee: If you’re not satisfied with your subscription, you can contact us for further help. Contact must be made within 3 business days of your subscription purchase and your refund request will be subject for review.

Please Note: Refunds can never be provided more than 30 days after the initial purchase date regardless of your activity on the site.