CHS 200, Chapter 12 Notes
CHS 200, Chapter 12 Notes CHS 200
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This 3 page Class Notes was uploaded by Shelby Sauer on Saturday October 8, 2016. The Class Notes belongs to CHS 200 at University of Nevada Reno taught by Dr. Logan Hamill in Fall 2016. Since its upload, it has received 5 views. For similar materials see Introduction to Public Health Biology in Biology, Chemistry, Community Health Sciences, Core Humanities, Nutrition at University of Nevada Reno.
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Date Created: 10/08/16
CHS 200 Chapter 12 Notes Note: Anything that is highlighted was either on a quiz or specifically noted by Dr. Hamill as content that will be on the exam. So know these! History of Fetal Alcohol Syndrome In 1968, Dr. Paul Lemoine in Nantes, France described 127children born to alcoholic mothers. • In late 1960’s, Dr. Christy Ulleland noted that children admitted for FTT were likely to have mothers with alcoholism. • In 1973, Drs. Jones, Smith, Ulleland & Streissguth published the constellation of similar physical and neurodevelopmental features in eight children born to alcoholic mothers in Lancet. • In 1974 the first case/comparison study was done using the Collaborative Perinatal Project subjects (n=55,000). –Children born to 23 alcoholic mothers (cases) were matched with 46 children born to non alcoholic mothers •4x increase in low IQ •8x perinatal mortality Physical Features • Growth deficiency –prenatal –postnatal • Facial anomalies –short palpebral fissures –flat midface –short upturned nose –smooth/long philtrum –thin upper lip • CNS damage –microcephaly –tremors –hyperactivity –fine/gross motor problem –attention deficits –learning disabilities –seizures –mental retardation First Epidemiologic Rubric 0.5 to 3/1000 births Up to 12,000 births with FAS/year in the U.S. Most common known nongenetic cause of mental retardation • 3040% of pregnant women who drink heavily (>1drink/day) Annual cost for the U.S. $75 million to $9.7billion Lifetime cost for caring for a typical child with FAS $1.4 million Mental retardation related to FAS 11% of US $ for institutionalized mental retardation Family costs immeasurable Second Epidemiologic Rubric Irish & Russian cultures are associated with heavy drinking French consume more ETOH per capita than any other country In the US, whites drink more than African American; Northerners>Southerners; younger>older adults; Catholics/Jews>Protestants; nonreligious>religious; urban>rural; large city>small city residents 60% women drink occasionally; 4% alcoholics • During pregnancy 20% drink occasionally; <1% heavy drinking Third Epidemiologic Rubric Four Results of Teratogen Exposure –death –malformations –growth deficiency –functional deficits Alcohol has been implicated in each type of negative outcome Alcohol exhibits a doseresponse relationship Fourth Epidemiologic Rubric Alcohol has a direct toxic effect on cells, producing cell death Impede the transport of amino acids & glucose Impair placentalfetal blood flow Disrupt control of neuronal cell maturation & migration Fifth Epidemiologic Rubric: Prevention 100% preventable Universal –Abstinence prior & during pregnancy –Information re: dangers of ETOH consumption –OB care Selective –Targeted intervention for women who drink ETOH & childbearing age –MD intervention Indicated –Interventions/Treatment aimed for the pregnant alcoholic –Engage significant others, friends & family