BIO 111 Chapter 11 Receptor Notes
BIO 111 Chapter 11 Receptor Notes BIO 111-08
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This 1 page Class Notes was uploaded by Chris on Tuesday October 11, 2016. The Class Notes belongs to BIO 111-08 at Ball State University taught by Dr. Metzler in Fall 2016. Since its upload, it has received 3 views. For similar materials see Principles of Biology (BIO 111, Dr. Metzler) in Biology at Ball State University.
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Date Created: 10/11/16
Receptor Tyrosine Kinase 1. The receptor monomers are just chilling 2. Signaling molecules attach to the binding sites a. The 2 monomers come together to form a dimer through dimerization 3. Each Tyrosine kinase of the dimer (6 total) are given an ATP which phosphorylates it into ADP, activating the dimer 4. Relay proteins attach to the phosphorylated tyrosines a. Cellular response ensues G Protein-coupled Receptor 1. G protein coupled receptor is empty a. G protein is inactive with GDP attached b. Enzyme is waiting for binding 2. Signaling molecule binds to G protein receptor a. G protein binds to receptor, changing GDP to GTP 3. The protein binds to the enzyme (adenylyl cyclase), activating it a. Cellular response from the enzyme 4. G protein goes back to normal with GDP attached again
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