BIO 203 Week Six Notes
BIO 203 Week Six Notes BIO 203LEC
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This 2 page Class Notes was uploaded by Andrea Tufekcic on Tuesday October 11, 2016. The Class Notes belongs to BIO 203LEC at University at Buffalo taught by Loretz, C A in Fall 2016. Since its upload, it has received 39 views. For similar materials see General Physiology Lec in Biology at University at Buffalo.
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Date Created: 10/11/16
Cardiovascular System Evolution Bkgrnd: multicellularity and tissue specialization require bulk transport of materials Organism Bkgrnd: distribution of respiratory gases, nutrients etc in an adaptive manner to suit physiological needs Health and Disease Bkgrnd: breakdown of homeostatic mech can jeopardize life (heart stops you die) adaptive responses to challenges can support survival Bulk Transport Systems: propulsive organs pressure reservoir and distribution (arteries) transfer systems (capillaries) blood reservoir and return system (veins) Types: open and closed OPEN CLOSED fluid hemolymph blood compartment Vessels/hemocoel vessels Compartment vol 30% of body volume 5-10% of body volume pressure 5-10 mmHg 75-150 mmHg Single circuit: one pass of fluid through the heart from start to finish Gills body Double circuit: two passes through heart from start to finish Lungs I know this isn’t good but I made it myself) Body Electrical response comes first, then muscular response In cardiac muscle: muscular response comes during refractory period of the action potential, which is longer -sinoatrial node fires first, spreads and contracts atrium -atrioventricular node fires and contracts ventricles -influx of Na and then Ca ions depolarizes pacemaker cells, threshold reach triggers huge calcium influx and subsequent action potential, K+ cell influx repolarizes the cell -norepinephrine causes rate of depolarization to increase and quickens heart rate -acetylcholine decreases rate of depolarization and slows heart rate Pressure/Volume Loop -constructed graphically from corresponding moment to moment values of pressure and volume ventricular emptying isometric Volume relaxation isometric contraction Left ventricular loop ventricular filling Pressure Pressure in ventricle must exceed pressure in aorta before emptying Frank-Starling Mechanism: mathematical system for establishing cardio output Cardiac Output (+) (+) Heart rate Stroke Volume (-) (+) (+) (+) Parasympathetic Sympathetic activity (and End diastolic volume activity epinephrine) (+) (+) Venous Laminar/Turbulent flow = smooth movement/lots of movement
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