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Ch 11 notes

by: Kathleen Quijada

Ch 11 notes BME3403 EABS

Kathleen Quijada
Broward College
GPA 3.46
Engineering analysis of biological systems EABS

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Engineering analysis of biological systems EABS
Class Notes
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This 8 page Class Notes was uploaded by Kathleen Quijada on Saturday April 18, 2015. The Class Notes belongs to BME3403 EABS at Florida International University taught by Dr.Brown in Fall2015. Since its upload, it has received 55 views. For similar materials see Engineering analysis of biological systems EABS in Biomedical Sciences at Florida International University.

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Date Created: 04/18/15
About this Chapter 39 Efferent division and what it controls Pathways receptors and neurotransmitters Antagonistic controls sympathetic and parasympathetic Control of cardiac smooth muscle some adipose tissue and glands in homeostasis CNS control of skeletal muscles through neuromuscularjunctions 7430013 swam W Newt Waggot39th 5139 oats ll 0 I WmPD sm c WWW ngi39mhw Prmvi mic sligyctghah 179on pm Agave mop n bl odds CWrxji Ulo liVLe o MOBSuhnic rawmas Autonomic Division Homeostatic balancing Autonomic Division Homeostatic balancing W M gt s am A 0 rm a g0 01 m 3 Qm39fAS fm fie 3y m Jaymehi Smooth amp cardiac muscle Glands amp adipose C CW A 1 m U 8 LL Respand39digw L a A u N 39 vilwquot 394quot i I l quot am 00 m uscbz quotRestgldigestquot Homeostasis Restore bodi v A A Pb Eaziiagggamic 39 quotFight or flightquot h S bi zu ggggnsic Energetic action quot Mmlmhsn ullm imaml 4 a V er1v A Figure quot1 iiumeosmis and lbc autonomic divisi0n Clhtu pi stN b w i Dr 14 m ih iu mm V R bgjrt 0 A 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to Au onomic Pathways Two Efferent Body Neurons Pom WWW m Ci i CO 1 r t 39 39 quot quotm HID 0 Cquot th CNS n Mjl t 39 I SM 50 W 5 auf n nkcl Preganglionic neuron S lWVFQHc 4 L Ganglion J7 39 3r 0 gLL hr NNVLS I l 51 o Postganglionic neuron li f awif i 39 mo quot h i Target tissue I B as quot low ox u g ram Umbic 1 39 h gt fem r S3610 trim 5533 Wb c 3 th at Liid m quot3 A I T s N g gum i J isQua l hm hw L 4 7 a Iiiglm ll I Autonomic pallmuys 39Autonomic b V 39 l J N g g Endocrine 39 Behavioral response V response 39 response A 4 a u a gt I M Figure l 12 The hymllmlmnus and brain slam initials nmononuc endocrine and behavioral responses ESfYEiEi LgW S hirxuixtttf CN 0P53 E1r 61593 5 513 1 Wil Atomt Bympmm na UWQSwawahk V hpa amphkc p pmpk oomm3wmpamdk Min Comparison of sympathetic and P th t B h quotR d D Parasympathetic Pathways arasympa em ranc39 ESt an 35 Sympathetic pathways Parasympathetic pathways N e u use norepinephrme use acetylcholtne Receptors CNS 39 32 estewsmg ties9r Originate in Brain stem Lower cord NT cholinergic 39 rv ACh v quot 39 39 39 39 w u mmw 7 t1v39 1 4 t A comm 4 CL chiLia 1th Sympm xhk ome 3 Neartarget 0 0100 CL tn tCBiHj Nicotinic receptors i Autonomic Autonomic ganglion ganglion 3 ngeprnephnne ACh 0 T Target tissue m ah tspihL db 5 I igmc 117 Sympathetic and pnmsynumtlmic pathways A Member WM quotHFC ht o mtk VCCCP mm Cm 39 A M captors Adrenerglc A receptor 39 USCCMratuk Vtcw ws 0 M A quotJ L L P WU WW POWC39L PU Atemos EVAPom Expquothabbth norept t nuin 4 lNPhYWLQ l 4 M5 cl iW t de39ivpcs Oil 33 GP SVWi aimWM Ill bUWW V Pupl mu saw7m K arm I m I 39139 p E quotquot a n L 218 M 37 m 8 W Wvu u 3 I E gtquot 4 m myus I y V143 m 1 6 mm 8 x 5 ram Q wanton WW 3 MM 0 39 M m 4 0quot O W I v VIMquot I M Q helm Q 0 a t quot ex on a w souum I 39 M M J W 39i luunlle l nttm L M M P G m y m 1 mun r nquot t wit q r 0 F M MI W Iquvnttax inlmuhfw u u m M c t t ANJKHIKE H H H Hair 0 J H nutuud mung quot N Yx thinni F A we A 10 M vim t nd39u nd 139 I39m n u M39 W U M a quotf39 lialJun 3313 t Wm S and 25 f w I I I quot 1quot t quot v a r39 L V m U and 39 r A spaa a m0 l tgurc 113 Aulunomlc sympathetic and utmsymmthuuc pn nmys c 13 x C M mym Fm L StrutL 39 quotPON quotQ0 bf W004 3 by m t NW to 9 momm a mm Amydo plumms uo SOK Actions of Parasympathetic Branch Jam Pupil Bronchioies W Digestion 4 clL CJ C Insulin release l test Urination Erections P r S P o n r 3h pol J dz PMA 59 M M hk Sym PcttC a a Massive demurein ch Examples of Autonomic Reflexes 39 Cold Water Whole Body Immersion causes tachycardia m Exposure of face to cold water causes bradycardia Mammalian Diving Reflex W via Vagal Nerve x Pupillary ReflexPupil Constricting in response to light Baroreceptor Reflex Low BP in carotid sinus results in tachycardia and blood vessel constriction Carotid Sinus Reflex Increased pressure within or external manipulation of m in bradycardia Dilation of Blood vessels as body temperature increases Secretion of epinephrine and norepine hrine from the adrenal medulla in response to ear or stress Sweating in response to increased body temperature bi atth turgid cm motM in W um tartrm L awful Sympathetic Branch quotFight or Flight Sympathetic chain Near spinal cord Long NT adrenergic WACPl Autonomic Effects on Cardiovascular System 2 heart rate 11 92 L 1 increases M2 decreases contractllity 51 1mm Increases M2 decreases B1 M2 Increases condudion decreases conduction increases cardiac muscle automaticityl Alrioventricular block 113 61 92 increases muactuin linotrogig increases cardiac muscle ammaticigl J m NUSCrMintc MW VS garagqmvwl QHc VCKSUCUlW i Smuo llo Poxch I QVM5 WC4 i Autonomic Effects on Blood Vessels Stimulatory Actions 0 Sympathetic Branch ulzm contacts 3253 relaxes all mnsmns 11 and 112m mnsiricu 1139 Inhibitory Actions of Sympathetic Branch Digestion V 3 A i htO a Pancreas secretion ahs39b o Urination 133 C9 8113 amt in gl39OdY 5 8X 1quotij 90 LOW cl t Milk Va melin i Ojlutwj n Blood vessels Bronchioles Adrenal Medulla A Modified Sympathetic Ganglion n v x 11 2 33 i 2 w 1 3quot ul39Qnglnl iist b 51 s 5quot quotnull irie Catecholamine release to blood Epinephrine Norepinephrine A if Travel to ePquot Multiple targets Distant targets quot a Y N quot L 0 H o m quotkiwi Lo qk i 34 itb m lWW39E DllWA Jr cwlrj lclgmllm QQW O mm NM W Adrenal Medulla A Modified Svmloathetic Ganglion a U096 Synapses inAutonomic Nerves Mnmrnsmx39ll39us Adrenal cortex IS a true endocrine gland 39a b r W 47 Vesicle conlalning 39 Adrenal medulla is a moddied quot neurolransmrlter Mltachondrron e 4 SVmpathetlr ganglion o N o cleft Ir391 J lg 12 I m 14 K0n 0 a N v I VE 1 L Iquot puslgangiionic y l I L V arge area r autonomic k quot Adrenal gland A a quot SiOW acting Q ll b l Long duration Blood vessel ACh 39 c A s quotV quot quot A g f4 m l V f r v I 39 39 quotquot7 a 4 I V Spinal 50rd v To target lissues r 39gt 59m mh L 39 l Smonlh muscle cell 1 Figure lllO The adrenal medulla W Figure llS Yaricoan ticsul uummnlc neurons ixrgltx HlLllciIJIllLL mm in rumJun Ilmilmlrl armmu quot j g WA 3 4 rugsl1 Mechanismi Norepinephrine Release and Review of Efferent Pathways Motor amp Rec clin Autonomic at new sl s y g m Adrenal symwtnellc Di Axon 0 39 w r MAO 39 bU 39 W 39 V Tyrosrne o Depolarrzzlllan 009m O 39 Ca enlry triggers Nlt0lmzc 39 39 exocylosrs of synaptic vesicles m uplo39 voltagegazed Cal channels MrLml caex Mrml medulla Aclron 7 opulence Voltagegated 7 v 0 NE blues to adrenergic Ca mannrel receolor on larger Caquot u A a D uses away e Aclrvny CC39JSES when NE dlllusos away lrcm ma synapso Blood vessel 0 NE 11 lransponed Back mic the axon ur w l u I 39 1 I 2 1 0 NE can no taken back Ir lo um I n 39 v l synamic vesicles in rerelease rr l n 1 l yr a KEY L NE is minimal my M AC up 0 NE morepr ruav quot M I I gtCOu manoam no u r1354 MAO h Kephy AU 3le we 1 V epnelquot m 3939E r I39vC rplwpll39 T Figure 119 errvmm nlnim relmse all n varicosin of a sympathetic neuron l lgwnplzj c mu Hum1 iucmhL X 2m pil fnlulw39l39l Immin l uzuwng 1 18quot l I mmn wy were Pam mys humming 1 SWQBW Lurcltar mong MNM MN Vamorums V A x QM 2th ithm mVj rclcmwu WW 3 i a139C yiM lm Um 3 f P th M n DIV mw l Cowmai Somatic Motor Division Controls Skeletal Neuronmuscular Junction Overvnew M u scles Body movement gm Appendages 3E Terminal boutons Locomotion 39 Synaptic Cleft S I Filled with a fibrous Matrix collagen 39 If e neuron V gCNs 39 AChE ct ll Llo llM Estwax longmd Hold axon terminal and motor end plate together M einate r On muscle BranChes buwm Nicotinic receptors Neuromuscularjunction m quot9 m I A Com boc cn 0139 4 kw and 3H she C Marcx p 03310 A Neuronmuscular Junction Mechanism of Signal Conduction Axon terminal AP signals ACh release Motor end plate Neuronmuscular Junction Overview will in lat Mr I i39ir39quot 11quot M mammals M Membrane depolarized a 4 f E39 7 l Stimulates fiber contraction a a 739 quot 3939 51 A a 4 l 39 a 5 e k vl 4 39v Inclms ACh L y 4 q 1 v mm H Wm mm Figure l112AnalomyoflbcnmuumusculmjuncLion NeuronmuscularJunction Summary Mechanism of Signal Conduction mmmmmm Autonomic branches sympathetic and parasympathetic Regulate glands smooth amp cardiac muscles Team with endocrine to regulate homeostasis Are regulated by hypothalamus pons amp medulla x mmmm Have pathways with 2 neurons and a ganglion m a w quot 1 I C Use varicosities to release NTs Ca9m9 m cm MJM39mne 39 Have diverse receptors tonic amp antagonistic regulation 139 1x atria 5413 93 Skeielalj uli it nu ACNE muscka ill Iquot I quotI i may l l l y b The nlcaunc choixnerg raceplcr bums Wm A55 ma39aculaa 1 h l l uer ma aoqnng a norspocm mumsMen canon channel I me J 1 v jN W V 1 Closed enamel receptor l39l 39 J I i 0quot Figure Hl 3 Ewnls m the neurommcular junction quotairmgln 321 um m 21m in mums l yumW lt n yn5 Efferent motor neurons control skeletal muscles Single long myelinated neuron from CNS Neuromuscular junction structure amp mechanism


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