HPHY 212 Week 4 Lecture Notes
HPHY 212 Week 4 Lecture Notes HPHY 212
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This 2 page Class Notes was uploaded by Scott Morrison on Wednesday April 22, 2015. The Class Notes belongs to HPHY 212 at University of Oregon taught by Dr. Andrew Karduna in Spring2015. Since its upload, it has received 109 views. For similar materials see Evidence, Inference and Biostatistics in Human Development at University of Oregon.
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Date Created: 04/22/15
HPHY 212 Lecture Notes Week 4 Footnote Chasing looking through the footnotes and citations of an article to find additional related material Pearling When newer articles build off of the foundation laid down by older articles like the layering process of the formation of a pearl MeSH Medical Subject Headings A hierarchical system of the organization of scientific articles 16 different major topics each with their own subtopics The same subtopic can exist in more than one major topic MeSH headings organize medical articles by assigning specific words Boolean Searches A search technique that allows the user to easily broaden or narrow the search results To make a search more specific use AND and NOT To make a search more broad use OR Vaccines and Autism How Levels of Evidence Relate to a Famous Scientific Controversy The Wakefield article an article published in Lancet a prestigious scientific journal The article involved a case series in which several less than 10 children with autism had developed their symptoms within a short period of receiving the MMR measles mumps rubella vaccine The Wakefield article led to a huge uproar about the use of vaccines on children The level of evidence of the Wakefield article was that of a case series one of the lowest levels on the spectrum It is also known that Wakefield fabricated an astonishing portion of his data Further study was done several meta analyses on the relationship of vaccines and autism have been done Each one has concluded that there is no link between the two Because several existing meta analyses point to the absence of a link between vaccines and autism and the only article that says otherwise is a case series a very low level of evidence especially compared to that of a meta analysis with fake data we can safely conclude that there is no link between vaccines and autism Yet tons of people are not vaccinating their children for fear of vaccinecaused autism because they do not do their research and they do not know their levels of evidence
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