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Bio 181 Cellular Overview and Enzymes

by: Victoria Smith

Bio 181 Cellular Overview and Enzymes BIO 181

Marketplace > Arizona State University > Biochemistry > BIO 181 > Bio 181 Cellular Overview and Enzymes
Victoria Smith
General Biology 1
Stout, Chakravadanula, Farrokh, Konikoff

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About this Document

These notes consists of the functions of enzymes, effects of delta G and outline of where we get energy
General Biology 1
Stout, Chakravadanula, Farrokh, Konikoff
Class Notes
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This page Class Notes was uploaded by Victoria Smith on Saturday February 27, 2016. The Class Notes belongs to BIO 181 at Arizona State University taught by Stout, Chakravadanula, Farrokh, Konikoff in Spring 2016. Since its upload, it has received 25 views. For similar materials see General Biology 1 in Biochemistry at Arizona State University.


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Date Created: 02/27/16
Cellular VW W Why do we eat To get make energy From Big to small energy released From small to big energy required Thermodynamics 0 1st Law energy is neither created nor destroyed 0 2nd Law it takes energy to impose order on a system Where do cells get energy 0 Photosynthesis and Respiration Energy comes from carbohydrates Anabolism vs Catabolism Metabolism anabolic reaction catabolic reaction 0 O smaller molecules larger molecule 0 O n O 06 000 larger molecule smaller molecules 2013 Encyclopaedia Britannica Inc Picture source Britannica o Anabolism is the combination of smaller molecules to former a bigger molecule Energy input is needed for anabolism o Catabolism is the breaking down of a bigger molecule to form smaller molecules Energy is released as the output Change in GgtO the reaction is endergonic Change in GltO the reaction is exergonic Metabolism Overview What is metabolism Sum of all total reactions Each reaction is catalyzed by an enzyme How Does ATP drive Endergonic Reactions ATP is hydrolyzed to form Ag and a phosphate group The phosphate group is transferred to a substrate Phosphorylation addition of a phosphate group this is called an exergonic reaction because the potential energy in ADP was much lesser than the one in the final product ADP P Activated Substrate The diagram below shows the difference between a reaction catalyzed by an enzyme and one which is not catalyzed by an enzyme Ueed Releeeed Energy Picture source WikiBooks Enzymes lower the activation energy of a reaction Difference between Change in G Change in GgtO the reaction is endergonic Change in GltO the reaction is exergonic How Do Enzymes Work Enzymes are catalysts All enzymes end with ase In order for reactions to occur reactants need to collide and have enough kinetic energy Enzymes do the following Bring the substrates together in the active site Bind using the quotlockandkeyquot method They provide lower activation energy Don39t change the energy released in the reaction Enzymes do not change DELTA G Flexible and dynamic Have enough kinetic energy to withstand the repulsion forces when the electrons of substrates interact They are catalysts unwrap999 Fquot martini2 s ARE tram EF E FlL mun out WEEK WWH LEiEt MH SHEETH NE Source Chem4kids 0 Transition State highest state in energy level when the substrate and enzyme bond together It is the least stable state during the reaction 0 Activation Energy kinetic energy required to strain the chemical bonds between to reach a transition state 0 Reaction rates depend on the kinetic energy and the activation energy Three Step Process of Enzymes of Enzyme Catalysis 1 Initiation enzymes bring along the substrates together to the active site 2 Transition State Facilitation the transition state is prevented thus lowering the amount of activation energy therefore speeding up the chemical reaction 3 Termination because products have less affinity than reactants they are less susceptible to the active site thus the products are released from the active site Notes by Victoria Smith


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