Week 1 PNB2264 notes; Histology and Skin powerpoint
Week 1 PNB2264 notes; Histology and Skin powerpoint PNB 2264
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This 5 page Class Notes was uploaded by Erica Jingozian on Thursday September 3, 2015. The Class Notes belongs to PNB 2264 at University of Connecticut taught by Kristen Kimball in Fall 2015. Since its upload, it has received 20 views. For similar materials see Human Physiology and Anatomy in Physiology at University of Connecticut.
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Date Created: 09/03/15
The Human Organism Anatomy structure Physiology function Hierarchy of Organization structure is adapted to function ex microvilli increase surface area of intestines therefore increase absorption effiencey Chemical level cellulartissueorganorgan systemljlorganism Homeostasis NOT equilibrium A DYNAMIC STEADY STATE small uctuations around a set point lntraceluar uid inside cells Extracellular interstitia uid bood plasma Feedback Control Mechanisms Integrating center control center EllIIIIllIllIllIllIllIllIllIllIllIllIll afferent pathway efferent pathway to the CNS away from CNS III lIllIl receptor Effector III lIllIl lIllIllIl stimulus Response Q Negative Feedback Negative Feedback Control EXAMPLE lbody temp is the stimulus l body temp is the response ex shivering Did our response affect our stimulus YES cosed loop because response affected stimulus negative feedback because response removed the stimulus IF You get cold and your blood vessels open up and you lose heat and get colder you still have feedback Response enhances stimulus variable change POSTIVE feedback EXAMPLE Room temp 30 C stimulus Decrease blood temp III sense change in blood temp receptor thermo receptors in skin also in brain to monitor blood temp I afferent neurons carry info to I brain hypothalamus integrating center Compares receptor info cold to set point normal I program response activate motor nerves efferent pathway skeletal muscle contractions EXAMPLE Smell food stimulus l mouth water response response does NOT affect stimulus NO feedback open loop quotfeed forwardquot Review Cosed loop negative feedback control keeps conditions relatively stable homeostasis cosed loop positive feedback control may promote useful change labor contractions blood clotting or disaster endstage circulatory shock Water no charge poar covalent bond electrons closer to oxygen atom H but overall neutral partially charge negative oxygen has a loose hydrogen bond with hydrogen atom Universal solvent Many compounds ionize electrolytes Reactivity High heat capacity thermal inertia hard to change temp of h20 humans thermo regulate Large heat of vaporization a lot of energy to change phase a lot of energy will get released Lubrication reduce heat build upprevent friction Cushioning can t compress it easily resisting compression helps joints HISTOLOGY AND SKIN goes along with powerpoint Will Cover epithelial connective muscle and nervous tissue Ep he al covers exposed surfaces lines internal passageways forms glands no intercellular material intercellularjunctions help connect cells apical surface free surface vs basal surface what s underneath is almost always connective tissue no blood vessels no blood supply to epithelial tissue have to rely on diffusion to get nutrient high regenerative property for exams think about structure and function relationships epithelial separate into classes by shape and layers squamous vs cuboidal vs columnar Connective cels extracellular matrix functions are binding support protection and insulation connective tissue proper cartilage bone IN DETAIL ON EXAM 1 specialized cells broblasts brocytes kill those amp you kill the tissue connective tissue proper quotblastquot cells actively secreting connective tissue matrix chondroblasts make cartilage chondrocytes cartilage osteoblasts osteocytes osteoclasts bone hemocytoblasts blood Matrix protein bers embedded in ground substance Fibers in Connective tissue CoHagenous shape cross linked helix protein collagen good at resisting stretch tensile strength ex scurvy lack of vitamin C defective collagen synthesis Eastic protein elastin stretching and recoiling extensibility random coil conformations Reticular bers protein reticulin gands deicate network supports individual cells in certain organs Ground substance in CT made up of interstitial uid adhesion proteins Loose CT Loose meshwork with all 3 bers Dense regular CT vs dense irregular CT colagen bers dermis of the skin ex tendons amp ligaments What property does collagen give dense CT Resist stretch SKA Epidermis epithelial l dermis connective tissue l hypodermis Epidermis Layer no blood supply dead keratinocytes Dermis Outer papillary layer areoar CT immune cells macrophages amp mast cells nner reticular layer exception dense irregular CT Hypodermis role is body s defense areoar CT Functions of Skin protect temperature regulation sensation vitamin D production some excretion blood reservoir this is up to slide 24 of Histology amp Skin powerpoint