Week 4 ANT 102
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This 1 page Class Notes was uploaded by Kelsey Gaudette on Thursday September 10, 2015. The Class Notes belongs to ANT 102 at Illinois State University taught by Fred Smith in Fall 2015. Since its upload, it has received 47 views. For similar materials see Human Origins in anthropology, evolution, sphr at Illinois State University.
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Date Created: 09/10/15
Adaptive advantages A Cystic brosis 1 Deleterious hereditary disorder characterized by excessive production of mucus in all organs notjust the lungs and malabsorption of nutrients 2 Most people die young in their 2039s3039s from lung failure you drown in your own uid 3 1 in 3900 children are born with cystic brosis 4 Several hundred mutations cause CF 5 Not speci c to any particular ethnic group 6 1 in 15000 mutation rate 7 Heterozygote advantage 8 Selective advantage i Asymptomatic and have signi cantly less frequent typhoid fever cholera e coli infections ii Because of the extra mucus and uids disease washes out of body more quickly than a normal body iii Carriers also more fertile iv Carriers less likely to develop breast cancer 9 Breast cancer i Suggestion that breast cancer is an infectious disease ii Always viral in lab animals iii Tumors always originate in milk ductsdirectly connected to external environment iv Breast cancer is differentially distributed throughout the world ex high in the US but low in Japan v Distribution of breast cancer mirrors the distribution of the house mouse I Point mutation that destroys the ability in the body to produce a certain enzyme that is necessary in metabolizing a certain amino acid ii Left untreated can cause problems with brain development leading to mental retardation and seizures iii One of the few genetic diseases that can be controlled by diet low in phenylalanine and high in tyrosine
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