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by: Darrion Bednar

Bioinformatics CISC436

Darrion Bednar
GPA 3.73


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About this Document

Class Notes
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This 5 page Class Notes was uploaded by Darrion Bednar on Saturday September 19, 2015. The Class Notes belongs to CISC436 at University of Delaware taught by LiLiao in Fall. Since its upload, it has received 44 views. For similar materials see /class/207172/cisc436-university-of-delaware in Computer Information Technology at University of Delaware.

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Date Created: 09/19/15
CISC 436636 Intro to Bioinformatics Spring 2008 Review session for MidTerm CISC636 SOS Reviewl Liao About the midterm closedbook Three parts Basic molecular biology 20 points Sequence alignments 45 points Hidden Markov models 35 points CISC636 SOS Reviewl Liao Basics of Molecular biology Central dogma Transcription Translation 0 Genetic code DNA Double helix Watsoncrick binding Genes Compositional Structure Reading frames Proteins Genome sequencing Sanger method CISC636 SOS Reviewl Liao Sequence alignments Motivations Concepts and assumptions Substitution scores Position independence Dynamic programming Problems can be dissect to subproblems Recurrence equations DP Table Traceback Global VS local alignments Pairwise VS multiple alignments Progressive approaches Score statistics EValue pValue CISC636 SOS ReVier Liao Hidden Markov models Motivations Concepts and assumptions Three tasks Decoding Viterbi algorithm Recurrence 0 Dynamic programming Model likelihood Forward algorithm Backword algorithm Recurrence 0 Dynamic programming Model building 0 Labeled data 0 Unlabeled data Viterbi training CISC636 SOS ReVier Liao


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