Week 3 notes
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This 11 page Class Notes was uploaded by Manuela N Tchamou on Tuesday September 22, 2015. The Class Notes belongs to Biology 3352 at Temple University taught by Dr. Stull in Summer 2015. Since its upload, it has received 41 views. For similar materials see Systems Neuroscience in Biology at Temple University.
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Date Created: 09/22/15
I 957ch hi7a Hpn Electrical Synapses vs Chemical Synapses A FLFCI RONIC SYNAPSE i Mmrolubulc ytopmm I rcsynaptic neuron Milochondrion Poslsynaplic Gap neuron junction Prcsynap c gnemhrs mg A 4 0 l 39 39 Postsynaptlc Gap junction membrane channels V VVC39 gt3 aP C 8 Cl H MICAI SYNAPSE Presynapti neuron Synaphc vesjdc Poslsynap c neuron mailman tun nanny um Mm Fogt r m h 04 7 ACng 3 M 9 vi 3 A 7 k J 4 35 3 33 wwz We c0291 06 coszEBH Ucm mwm mm mammmxoma nmww t m 930E mogtgt 9 2 l iamsal saam V 25 E E 1 rs mmw m m WM 1 L 0 a lt39 AL mpg yh JG 3 1 amp Exocytosis Secretory Granules Sm molecule neuro lr 39 lt l39 m small clearvmn csiclm xd muse In concentration Highrrqucnq sumulnllon Nmmpep do in 11th densocam vesich lam Lynch Postsynaptic Response JsLllUll in quotll P54 jmpho Receptors and Results image J A Hj 4 0 Wt v 4W 1 H x 8 V 0 Types mkvblh j 39 l lt t 3 Ionotropic transmitterjgated ion channels Po SV QFHC Metabotropic Gproteln coupled receptors Weak Results l r 4 3 km EPSP transient postsynaptic membrane 39 I a depolarization by presynaptic release of quot quotiv 1vl neurotransmitter EXCITATORY IPSP transient hyperpolarization of postsynaptic l l I 1 membrane potential caused by presynaptic release of l quot neurotransmitter 11 oi n EL Jm Al l GProteinCoupled or Metabotropic C g Receptors Steps of neurotransmitter action Bind to receptor proteins Activate small proteins Activate effector proteins Results slower longlasting and fartherreaching effects Truxwum b Ion m Humanm Bonnquot M Dunn m Ed Connos AM Pancho cumin 01007 Upplnuammamlm The Gene ation of an IPSP Jam neg zerw I v 4 Nwmxtnmm mov 194ev l 11 I 1 gquot 394 lt aquot 1 l 53949 Some 144303 ak a m hawt ngmx skmlakm 54 V an k Neural Integration Summa om Excitatory or inhibitory mmzmmta gxiiquot 33 A um hi mk A Neurotransmitter Receptors Effectors and Results Summary One transmitter at 1 synapse may activate lonotropic fast receptors andor Metabotropic slow receptors One transmitter may elicit depending on the receptor EPSPs IPSPs Agonists andor antagonists may act at receptors in some capacity Autoreceptors allow for self regulation MAW we lie Wmt mnsmukr Mud3 is Noam pm Egon Aryan 5 s oakV aer re Qp 3 block 2 NEURC lSClENCE Chapter Exploring the Brain Neurotransmitter SySYGmS Neuroscience Exploring the Bram by Mark F Bear Barry W Connors and Michael A Paradise Elements of Neurot ansmitter Systems Prosynap c axon lermlnal Neumlransmmer ynmesizing enzymes 39 I synaplic ves mIe lranseoners Reuptako lmnsponem If Degradalive enzymes 39 V M Transmittergated ion channels Gprotemcouple veceplors Gpvolexns Poslsynapllc Gorochngamd son channels dendrlle Secmd messenger cascades Some 144303 ak a m hawt ngmx skmlakm 54 V an k Neural Integration Summa om Excitatory or inhibitory mmzmmta gxiiquot 33 A um hi mk A NMDA 3 new Differential Activation of AM PA W 391 1 p L Humanman Exploring in main 3nd Ed Bun cannon And Panam copyrigmozom Upplnoonwlllumxswmm l i v V o 2 4 a a Time WW action potential mm e en a Edam U xi quot i i ifV and NMDA Receptors AMPA only 0 25 NMDA only 23 oqw libn39w39q m th xiglg i3 kl LO I A is 62 brag which bd wezn wig
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