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Bio Notes- Week of Sept 21

by: Caroline Emery

Bio Notes- Week of Sept 21 BIOL 160 - 018

Caroline Emery
GPA 3.49
Cellular and Molecular Biology
John W Koontz

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About this Document

Inner working of the cell, endomembrane system, organelles, catalysis, enzymes
Cellular and Molecular Biology
John W Koontz
Class Notes
endomembrane system, Biology, bio 160, organelles, Catalysis, Enzymes
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This 4 page Class Notes was uploaded by Caroline Emery on Friday September 25, 2015. The Class Notes belongs to BIOL 160 - 018 at University of Tennessee - Knoxville taught by John W Koontz in Fall 2015. Since its upload, it has received 38 views. For similar materials see Cellular and Molecular Biology in Biology at University of Tennessee - Knoxville.


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Date Created: 09/25/15
922 Endomembrane System 0 Rough ER 0 Ribosomes 0 New proteins are folded and processed in the rough ER lumen Smooth ER 0 Synthesize fatty acids 0 Break down poisonous lipids 0 Storage for Ca Golgi Complex 0 Processes sorts and ships proteins from the rough ER 0 Cis side faces the nucleus 0 Enters cis side exits trans side 0 Each protein has a molecular tag that signi es what kind of transport vesicle it needs Signal Hypothesis Predicts that proteins have a quotzip codequot 0 ER signal sequences bonds to SRP signal recognition partical then binds to a receptor in the ER membrane 0 ln lumen of RER proteins are folded and glycosated o Carbs are attached to the protein Exocytosis Vesicles sent to cell surface in vesicles that fuse with the plasma membrane PulseChase Audioradiography o Allows to gure out where radioactive particles by exposing undeveloped xrays to the molecules being studied Handout Lysosomes Single membrane bound structure with lots of enzymes Mitochondria Two membranes 0 Inner one is cristae folded membrane mitochondrial matrix is inside 0 Has their own DNA and make their own ribosomes Chloroplasts Double membrane 0 Has their own DNA Photosynthesis o Thylakoids membrane bound at vesicles into piles caed gana 0 Outside thylakoids is stroma 924 Energy 0 Kinetic energy of motion 0 Potential stored energy chemical energy energy of position 0 Free Reactions Exothermic reaction releases energy AG lt 0 products have less potential energy than reactants Endothermic reaction requires energy AG gt O reactants have less potential energy than products Entropy AS amount of disorder Spontaneity AG gt O spontaneous exergonic AG lt O not spontaneous needs energy input endergonic AG O l at equilibrium Reaction coupling Combining an endergonic reaction with an exergonic one to drive the endergonic one Catalysis Protein functions Accelerates the rate at which equilibrium is reached 0 Catalyst lowers the activation energy 0 AE amount of free energy required to reach transition state 0 Reactions only occur when transition state is reached 0 This increases the rate of reaction 0 Lowers free energy of the of the transition state 0 DO NOT CHANGE AG and are not consumed in the reaction 0 Reaction velocity reaches terminal speed when the catalyst is saturated 0 Speed is dependent on enzyme concentration Enzymes Inhibitors 0 Competitive binds to the same site as the substrate


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