New User Special Price Expires in

Let's log you in.

Sign in with Facebook


Don't have a StudySoup account? Create one here!


Create a StudySoup account

Be part of our community, it's free to join!

Sign up with Facebook


Create your account
By creating an account you agree to StudySoup's terms and conditions and privacy policy

Already have a StudySoup account? Login here

Neuronal Membrane Channels

by: Emma Notetaker

Neuronal Membrane Channels NSCI 3310

Marketplace > Tulane University > Neuroscience > NSCI 3310 > Neuronal Membrane Channels
Emma Notetaker
GPA 3.975

Preview These Notes for FREE

Get a free preview of these Notes, just enter your email below.

Unlock Preview
Unlock Preview

Preview these materials now for free

Why put in your email? Get access to more of this material and other relevant free materials for your school

View Preview

About this Document

notes on neuronal membrane channels
Cellular Neuroscience
Jeffrey Tasker
Class Notes
25 ?




Popular in Cellular Neuroscience

Popular in Neuroscience

This 3 page Class Notes was uploaded by Emma Notetaker on Tuesday September 29, 2015. The Class Notes belongs to NSCI 3310 at Tulane University taught by Jeffrey Tasker in Summer 2015. Since its upload, it has received 31 views. For similar materials see Cellular Neuroscience in Neuroscience at Tulane University.

Similar to NSCI 3310 at Tulane


Reviews for Neuronal Membrane Channels


Report this Material


What is Karma?


Karma is the currency of StudySoup.

You can buy or earn more Karma at anytime and redeem it for class notes, study guides, flashcards, and more!

Date Created: 09/29/15
Neuronal Membrane and Ion Channels 09/02/2015 ▯ ionic environments  aqueous: o H2O – polar o positive and negative poles  salts: NaCl, KCl, CaCl2 o dissolve in h2o o form ions o Na+, K+, Ca@+, Cl- o same for both intra and extracellular enviironments ▯ phospholipid bilayer  two layers/sheets of amphipathic [hospholipids o polar/watter attracting head o non-polar, water-repelling tail  impermeable to charged particles o outer leaflet is POLAR – prevents ions from crossing o energy required for ions to cross  plasma membrane ▯ membrane components:  membrane proteins – facilitate ion and info flow acorrs membrane o integral – amphipathic and span intra to extra cellularly  ion channels  ion pumps o peripheral: located to one side of the membrane  G proteins  cholesterol – determines membrane fluidity  carbohydrates: how cells interact with other cells and proteins o glycolipids – interact with matrix and other cells o glycoproteins – protein-protein interaction ▯ membrane protein structure:  primary – amino acid chain (linked by peptide bonds) o amino acids classified as hydrophobic (will stay in membrane) or hydrophilic (organize on end of membrane to touch water) o classified by R group  secondary – alpha helix and B sheet  tertiary – protein folding o complete protein (ONE amino acid chain)  quaternary – association of MULTIPLE tertiary structures o THESE are the actual membrane proteins o VERY rarely will an actual membrane proteins only one strand ▯ membrane protein function:  ion channels (ionotropic receptors) – pores, gated and selective  transporters – ion pumps and carriers, ATP-dependent  metabotropic receptors – trigger intracellular reactions (2 nd messenger cascades)  cell interactions – junctions, adhesion, migration and maturation ▯ ion channel:  ion selective o ion filter o Na+, K+, CA2+, Cl- o possible mechanisms that determine selectivity:  charge  size  water (what water is attaching to)  gated o not open all the time – open and close  localized general conformational change (changes shape to close pores  ball and chain model – protein blocks gate o can have multiple gates per channel  Types: divided based on how the gates are opened o leak – open all the time  flux ions at very slow rate (like a faucet) o ligand-gated:  dependent on neurotransmitters (ligands)  ionotropic receptor nd o 2 messenger-gated  dependent on phosphorylation (add phosphate group to channel, causes it to open)  dependent on G protein o voltage-gated:  dependent on membrane potential  voltage sensors of the cell o mechanically gated  sensitive to stretch of membrane  often in peripheral nervous system (touch receptors)  ion pumps and transporters  proteins use ATP in order to move ions o expend energy – active process  Na+/K+ pump (video on slide) o ATPase (because it uses ATP) – P group binds to receptor on pump o pumped 3 Na OUT, 2 K IN (per ATP) o maintains membrane potential – creates concentration gradient o net charge inside the cell is NEGATIVE o when K binds, dephosphorylated pump ▯ ▯


Buy Material

Are you sure you want to buy this material for

25 Karma

Buy Material

BOOM! Enjoy Your Free Notes!

We've added these Notes to your profile, click here to view them now.


You're already Subscribed!

Looks like you've already subscribed to StudySoup, you won't need to purchase another subscription to get this material. To access this material simply click 'View Full Document'

Why people love StudySoup

Bentley McCaw University of Florida

"I was shooting for a perfect 4.0 GPA this semester. Having StudySoup as a study aid was critical to helping me achieve my goal...and I nailed it!"

Kyle Maynard Purdue

"When you're taking detailed notes and trying to help everyone else out in the class, it really helps you learn and understand the I made $280 on my first study guide!"

Bentley McCaw University of Florida

"I was shooting for a perfect 4.0 GPA this semester. Having StudySoup as a study aid was critical to helping me achieve my goal...and I nailed it!"

Parker Thompson 500 Startups

"It's a great way for students to improve their educational experience and it seemed like a product that everybody wants, so all the people participating are winning."

Become an Elite Notetaker and start selling your notes online!

Refund Policy


All subscriptions to StudySoup are paid in full at the time of subscribing. To change your credit card information or to cancel your subscription, go to "Edit Settings". All credit card information will be available there. If you should decide to cancel your subscription, it will continue to be valid until the next payment period, as all payments for the current period were made in advance. For special circumstances, please email


StudySoup has more than 1 million course-specific study resources to help students study smarter. If you’re having trouble finding what you’re looking for, our customer support team can help you find what you need! Feel free to contact them here:

Recurring Subscriptions: If you have canceled your recurring subscription on the day of renewal and have not downloaded any documents, you may request a refund by submitting an email to

Satisfaction Guarantee: If you’re not satisfied with your subscription, you can contact us for further help. Contact must be made within 3 business days of your subscription purchase and your refund request will be subject for review.

Please Note: Refunds can never be provided more than 30 days after the initial purchase date regardless of your activity on the site.