New User Special Price Expires in

Let's log you in.

Sign in with Facebook


Don't have a StudySoup account? Create one here!


Create a StudySoup account

Be part of our community, it's free to join!

Sign up with Facebook


Create your account
By creating an account you agree to StudySoup's terms and conditions and privacy policy

Already have a StudySoup account? Login here

Bio 110 Epigenetics

by: Heer Patel

Bio 110 Epigenetics 110

Marketplace > University of Massachusetts > Biology > 110 > Bio 110 Epigenetics
Heer Patel
GPA 4.0
Introductory Biology for non-Science Majors
Christiane Healey

Almost Ready


These notes were just uploaded, and will be ready to view shortly.

Purchase these notes here, or revisit this page.

Either way, we'll remind you when they're ready :)

Preview These Notes for FREE

Get a free preview of these Notes, just enter your email below.

Unlock Preview
Unlock Preview

Preview these materials now for free

Why put in your email? Get access to more of this material and other relevant free materials for your school

View Preview

About this Document

Introductory Biology -- This set of notes includes Genetic Applications, Epigenetics, Gene Therapy, Regenerative Medicine, and Stem Cells and Cloning Enjoy!
Introductory Biology for non-Science Majors
Christiane Healey
Class Notes
#Biology #Genes #Cells #Epigenetics #StemCells #Cloning #GeneticApplications #Bio
25 ?




Popular in Introductory Biology for non-Science Majors

Popular in Biology

This 4 page Class Notes was uploaded by Heer Patel on Friday October 9, 2015. The Class Notes belongs to 110 at University of Massachusetts taught by Christiane Healey in Spring2015. Since its upload, it has received 42 views. For similar materials see Introductory Biology for non-Science Majors in Biology at University of Massachusetts.

Similar to 110 at UMass

Popular in Biology


Reviews for Bio 110 Epigenetics


Report this Material


What is Karma?


Karma is the currency of StudySoup.

You can buy or earn more Karma at anytime and redeem it for class notes, study guides, flashcards, and more!

Date Created: 10/09/15
GENETIC APPLICATIONS DNA Fingerprinting Human Inheritance brief overview 2 copies of each chromosome diploid Homologous chromosomes Humans 1n 23 2n 46 Each chromosome pair One from mother One from father For any given geneocated on a given chromosome Two copies One from father one from mother Gel Electrophoresis can distinguish between the size of DNA fragments EPIGENETICS Production of a recombinant DNA molecule makes use of which of the following principles of DNA structure and chemistry Complementary singlestranded nucleic acid sequences can come together to form a duplex molecule A restriction enzyme cleaves duplex DNA molecules only at the positions of certain short sequences constituting the enzyme39s restrictions site DNA ligase is an enzyme that can join the ends of single stranded DNA molecules A DNA fragment migrates through an agarose gel according to its size Small fragments migrate faster closer to the positive electrode than large fragments Epigenetic The study of changes in organisms caused by modi cation of gene expression rather than alteration of the genetic code itself The study of stable longterm alterations in the transcriptional potential of a cell Epigenetic modi cations Chemical groups attach to DNA or to proteins around which the DNA is wrapped Only particular genes are modi ed Those genes are silenced longterm Silenced not expressed Not transcribed and translated We have many different types of cells in our bodyhow can that be Different cells have different parts of their DNA silenced by epigenetic modi cations and the active parts determine a cells39 identity GENE THERAPY What is gene therapy Introducing a functional gene into someone who carries a faulty version First death as a consequence of a gene therapy trial Jesse Gelsinger 1999 Death because reaction to vector not inserted gene itself US Food and Drug Administration Cellular and Gene Therapy Products Human gene therapy refers to products that introduce genetic material into a person39s DNA to replace faulty or missing genetic material thus treating a disease or abnormal medical condition The Center for biologics Evaluation and Research CBER regulates ceuar therapy products human gene therapy products and certain devices related to cell and gene therapy Although some ceuar therapy products have been approved CBER has not yet approved any human gene therapy products for sale REGENERATIVE MEDICINE Cell based therapy What are Stem Cells Unique cells that Can selfrenew for the life time of an organism Self renew reproduce without changing developmental potential Are unspecialised Can give rise to specialized cell types Self renewal requires cell division Progressive restriction of differentiation potential Fertilization gt Totipotent cells gt Blastocyst gt Fetus gt Adult Embryonic Adult and iP Stem Cells Embryonic SC They are pluripotent Derived from inner cell mass from 35 day old blastocyst Human blastocyst come from lVF clinics Adult SC Multipotent Rare in body Derived from fetal or adult tissues lnduced pluripotent SC Reprogramming differentiated cells lnto ESC like cells To date not completely reprogrammed STEM CELLS AND CLONING Zygote Totipotent The Fourcell stage when the zygote has divided into four cells Totipotent Stem cells in the bone marrow of your neighbours Multipotent Embryonic stem cells Pluripotent What would happen If you inject ESC into an immunosuppressed mouse let39s assume that the cells can survive ESC would generate tissues needed in the mouse Turn into a human body part The injected area would turn into a tissue with blood vessels Turn into weird tumors with all types of tissues


Buy Material

Are you sure you want to buy this material for

25 Karma

Buy Material

BOOM! Enjoy Your Free Notes!

We've added these Notes to your profile, click here to view them now.


You're already Subscribed!

Looks like you've already subscribed to StudySoup, you won't need to purchase another subscription to get this material. To access this material simply click 'View Full Document'

Why people love StudySoup

Bentley McCaw University of Florida

"I was shooting for a perfect 4.0 GPA this semester. Having StudySoup as a study aid was critical to helping me achieve my goal...and I nailed it!"

Jennifer McGill UCSF Med School

"Selling my MCAT study guides and notes has been a great source of side revenue while I'm in school. Some months I'm making over $500! Plus, it makes me happy knowing that I'm helping future med students with their MCAT."

Jim McGreen Ohio University

"Knowing I can count on the Elite Notetaker in my class allows me to focus on what the professor is saying instead of just scribbling notes the whole time and falling behind."

Parker Thompson 500 Startups

"It's a great way for students to improve their educational experience and it seemed like a product that everybody wants, so all the people participating are winning."

Become an Elite Notetaker and start selling your notes online!

Refund Policy


All subscriptions to StudySoup are paid in full at the time of subscribing. To change your credit card information or to cancel your subscription, go to "Edit Settings". All credit card information will be available there. If you should decide to cancel your subscription, it will continue to be valid until the next payment period, as all payments for the current period were made in advance. For special circumstances, please email


StudySoup has more than 1 million course-specific study resources to help students study smarter. If you’re having trouble finding what you’re looking for, our customer support team can help you find what you need! Feel free to contact them here:

Recurring Subscriptions: If you have canceled your recurring subscription on the day of renewal and have not downloaded any documents, you may request a refund by submitting an email to

Satisfaction Guarantee: If you’re not satisfied with your subscription, you can contact us for further help. Contact must be made within 3 business days of your subscription purchase and your refund request will be subject for review.

Please Note: Refunds can never be provided more than 30 days after the initial purchase date regardless of your activity on the site.