New User Special Price Expires in

Let's log you in.

Sign in with Facebook


Don't have a StudySoup account? Create one here!


Create a StudySoup account

Be part of our community, it's free to join!

Sign up with Facebook


Create your account
By creating an account you agree to StudySoup's terms and conditions and privacy policy

Already have a StudySoup account? Login here

Human Physiology Laboratory

by: Dessie Botsford

Human Physiology Laboratory BIO 378

Marketplace > Eastern Kentucky University > Biology > BIO 378 > Human Physiology Laboratory
Dessie Botsford
GPA 3.94

Gary Ritchison

Almost Ready


These notes were just uploaded, and will be ready to view shortly.

Purchase these notes here, or revisit this page.

Either way, we'll remind you when they're ready :)

Preview These Notes for FREE

Get a free preview of these Notes, just enter your email below.

Unlock Preview
Unlock Preview

Preview these materials now for free

Why put in your email? Get access to more of this material and other relevant free materials for your school

View Preview

About this Document

Gary Ritchison
Class Notes
25 ?




Popular in Course

Popular in Biology

This 7 page Class Notes was uploaded by Dessie Botsford on Sunday October 11, 2015. The Class Notes belongs to BIO 378 at Eastern Kentucky University taught by Gary Ritchison in Fall. Since its upload, it has received 7 views. For similar materials see /class/221462/bio-378-eastern-kentucky-university in Biology at Eastern Kentucky University.


Reviews for Human Physiology Laboratory


Report this Material


What is Karma?


Karma is the currency of StudySoup.

You can buy or earn more Karma at anytime and redeem it for class notes, study guides, flashcards, and more!

Date Created: 10/11/15
B10 378 Lecture 7 Skeletal Muscle A Structure of Muscle Fiber and Myo laments 1 attached to Bones by Tendons connective tissue 2 muscle is made up ofmuscle bers Perimysium Bone Blood Vessels Endomysium Muscle Fiber Cell Tendon EPimEi m Fassicle Endom ysium 3 each muscle ber is composed of myo brils myo laments H c 11quot Ending 4 There are two types of myo laments lt V Sarcomere Myosin Lattice mm g Immest SW Networks a Thick myofilaments are made of MYOSIN have myosin heads which have ATP binding sites b Thin myo laments are made of three proteins 1 Actin have binding sites for Myosin heads 2 Troponin 3 Tropomyosin 5 These myo brils myo laments have distinct banding patterns Sarcomere a A band Dark dense portion where thick and thin laments overlap b H zone Central area where there are only thick laments c I band Light area between A band and Z line where there are only thin laments d Z line Dark line separating sarcomeres 6 Skeletal muscles have a Sarcoplasmic Reticulum SR Sarcoplasmic Reticulum Saroolomma Myo brils Terminal cisternae Transverse lu Dule Sarcoplasmic reticulum Mitochondria 4 a similar to ER of other cells b SR is c stores Calcium Ions d The SR has calcium gates that pump calcium via active transport into the SR from the cytoplasm of the muscle cell B In a relaxed muscle 1 Calcium gates are closed therefore calcium stays in the SR 2 there is a very high concentration of calcium in the SR and very low concentration of Ca in the cytoplasm 3 the binding sites for the myosin heads on the actin laments are covered by Tropomyosin C Muscle contraction l A nervous impulse depolarizes the SR and causes calcium gates to open 2 Calcium ions diffuse rapidly out of the SR into the cytoplasm 3 The calcium binds to a binding site on the Troponin molecules 4 When a calcium ion lls this site it causes a change in the shape amp position of the Troponin When the Troponin shifts if pulls the Tropomyosin to which it is attached 5 Movement of the Tropomyosin permits the Myosin head to contact the Actin 6 Contact of Myosin head with Actin causes the ATP molecules to break down to ADP THIS RELEASES ENERGY 7 The release of energy causes the myosin head to swivel forward During the swivel the Myosin head is rmly attached to Actin When the head swivels it pulls the Actin and the entire thing myofilament forward Many Myosin heads are swivelling simultaneouslytheir collective efforts are enought to pull the entire thin myofilament 8 At the end of the swivel the ATP has completely broken down to ADP a Thus the Myosin head ATP sites are empty and the Myosin head cannot maintain its attachment to Actin b Therefore the Myosin head swivels back into the starting position c however lots more ATP are starting to fill the ATP binding sites because 9 By the time the Myosin head has swivelled back the ATP binding sites have been refilled As a result the Myosin head can once again bind firmly to the Actin MymiN mmphx Ammllrh39x Tlml39mna m ATP 5 I 12 1 1119mm A3 my 10 M Eancmsshxdge 3D Ammauan 11 When the hmnusimpulse stops than the calmum gates close 12 on the Tropomn molecules W1thoutCaTropomn retums tons ongmal shape and head and hem and therefore the muse1e stops contracting relaxes 11 As A 1 1h Am and swwel ef nently Thxs deehne m ATP levels m a musele causes So dunng contraction 1 z lmes eome closer 2 deth ofA bands decreases 3 deth ofH zones decreases 4 Therexsno change m the wxdth ofthe I bands Useful links Human Physiology Muscle Muscles Back to B10 378 Syllabus


Buy Material

Are you sure you want to buy this material for

25 Karma

Buy Material

BOOM! Enjoy Your Free Notes!

We've added these Notes to your profile, click here to view them now.


You're already Subscribed!

Looks like you've already subscribed to StudySoup, you won't need to purchase another subscription to get this material. To access this material simply click 'View Full Document'

Why people love StudySoup

Bentley McCaw University of Florida

"I was shooting for a perfect 4.0 GPA this semester. Having StudySoup as a study aid was critical to helping me achieve my goal...and I nailed it!"

Anthony Lee UC Santa Barbara

"I bought an awesome study guide, which helped me get an A in my Math 34B class this quarter!"

Jim McGreen Ohio University

"Knowing I can count on the Elite Notetaker in my class allows me to focus on what the professor is saying instead of just scribbling notes the whole time and falling behind."


"Their 'Elite Notetakers' are making over $1,200/month in sales by creating high quality content that helps their classmates in a time of need."

Become an Elite Notetaker and start selling your notes online!

Refund Policy


All subscriptions to StudySoup are paid in full at the time of subscribing. To change your credit card information or to cancel your subscription, go to "Edit Settings". All credit card information will be available there. If you should decide to cancel your subscription, it will continue to be valid until the next payment period, as all payments for the current period were made in advance. For special circumstances, please email


StudySoup has more than 1 million course-specific study resources to help students study smarter. If you’re having trouble finding what you’re looking for, our customer support team can help you find what you need! Feel free to contact them here:

Recurring Subscriptions: If you have canceled your recurring subscription on the day of renewal and have not downloaded any documents, you may request a refund by submitting an email to

Satisfaction Guarantee: If you’re not satisfied with your subscription, you can contact us for further help. Contact must be made within 3 business days of your subscription purchase and your refund request will be subject for review.

Please Note: Refunds can never be provided more than 30 days after the initial purchase date regardless of your activity on the site.