Clin Pshy Hlth Prof
Clin Pshy Hlth Prof HSC 3549
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This 4 page Class Notes was uploaded by Charlotte Wolf on Monday October 12, 2015. The Class Notes belongs to HSC 3549 at Florida International University taught by Daniel Castellanos in Fall. Since its upload, it has received 53 views. For similar materials see /class/221756/hsc-3549-florida-international-university in Health Sciences at Florida International University.
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Date Created: 10/12/15
CHAPTER 10 PRESSURE amp BVS Arteries Blood pressure force exerted by the blood against a vessel wall depends on volume and compliance of vessels Arteries orapid transit for blood pressure reservoir elastic vessels lined With sm muscle otwo types of connective tissue elastin elastin collagen strength Diastolic P 13 pulse pressure This is monitored by BP receptors Arterioes ornajor resistance vessel ocreates pressure differential olittle elastic but lots 0 sm muscle Muscle Autoreulation dec 02 oinc C02 oinc H oinc K oinc osmolarity oAdenosine release Capillaries EDRFINO inhib Ca induced smooth muscle contraction ie vasodilation Endothelin vascocontriction Diffusion Pressure at Capillary Bed Due to hydrostatic pressure P amp oncotic or colloid pressure B The diffusion of H20 through a semipermeable membrane Higher H20 concentration to a lower H20 concentration H20 moves by osmosis to a region where the solute concentration is higher Bulk Flow Due to hydrostatic pressure P 39 by FLUD amp oncotic colloid pressure 3 by PAR TICLES Outward into tissue Plasmacapillary BP uid hydrostatic pressure PC Interstitial uidcolloid pressure B little effect because WHY Inward into the capillary Interstitial uid pressure hydrostatic pressure P little effect also because WHY Plasma colloid pressure oncotic pressure Bp Net Exchange Pressure outward inward Lymphatic System Returns excess uids Defense against disease destuction of bacteria in lymph nodes by specialized phagocytic cells Transport of absorbed dietary fat end products of digestion are transported via lymph system Returns ltered protein Edema accumulation of interstitial uid oreduced plasma proteins less oncotic pressure less fluid absorbed oinc perm of capillaries to plasma proteins histamine released due to injury or allergy blockage of lymph vessels elephantitis olnc venous pressure congestive heart failure pregnancy Venous Return Sympathetic Activity Skeletal Muscle counter gravity Venous valves Respiratory activity Cardiac Suction Veins ow resistance blood reservoir thinner walls less sm muscle nave little elasticity vs arteries collagen is more abundant than elastin ANS Receptors Cholinergic Ach Adrenergic Epi NorEpi Hypertension and H ypotension above 14090 mmHg 90 cases of unknown etiology 1quot or essential hypertension Defects in NaCl management by kidneys Excessive NaCl intake Low intake fruitsveggies KquotCaH arteriolar relaxation Defective NalK pumps impfor NaCI mgmt in kidneys Faulty gene for angiotensinogen NaCI amp H20 reabsorbtion endogenous digitalislike substances inc cardiac contractility obesity abnormalities in locally acting vasoactive cmpds NO pg 334 endothelin vasoconstrictor Hypertension and Hypotension above 140l90 mmHg 10 cases of known etiology 20 Hypertension Cardiovascular inc TPR arthrosclerosis Renal occlusion of renal a inc Angiotensin II inc H20 in blood vol tissue damage Endocrine pheochromocytoma adrenal tumor inc levels of epi and Norepi catecholamines Conn s syndrome adrenal cortical overproduction of aldosterone inc NaCl H20 retention Neurogenic neural lesion CV centerbarroreceptors compensatory resposne to local constriction Hypertension and H ypotension below 10060 mmHg Transient orthostatic hypotension failure to compensate for gravity when moving from horizontal to vertical decrease in venous return Emotional fainting higher brain centers dec sympathetic tone to vessels vasodilation dec TPR venous pooling
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