BIOL FOR SCI MAJ II
BIOL FOR SCI MAJ II BIOL 1202
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This 12 page Class Notes was uploaded by Charles Kohler on Tuesday October 13, 2015. The Class Notes belongs to BIOL 1202 at Louisiana State University taught by Steve Pollock in Fall. Since its upload, it has received 37 views. For similar materials see /class/222816/biol-1202-louisiana-state-university in Biological Sciences at Louisiana State University.
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Date Created: 10/13/15
HardyWeinberg Equilibrium The population genetics theorem that states that the frequencies of alleles and genotypes in a population will remain constant unless acted upon by non Mendelian processes See fig 237 and 238 Parent population a a Genotypes HR Hr rr Number of 320 160 20 total 500 Parent population e e Genotypes RH Hr rr Number of 320 160 20 total 500 Parent population e e Genotypes RH Hr rr Number of 320 160 20 total 500 Number of 6405 1605 160 Mr alleles in gene pool total 1000 Parent population e a RR R rr Genotypes Number of 320 160 20 total 500 Number of 6405 1605 160r 40r alleles in gene pool lolal 1000 Allele 500 200 lrequencies 1000 0398 R 1000 0392 r p frequency of H 08 q lrequency ol r 02 This means that 80 of sperm amp eggs will carry R an 20 of sperm amp eggs will carry r Allele Frequencies Under strict Mendelian inheritance allele frequencies would remain constant from one generation to the next HardyWeinberg Equilibrium 80 p08 02 Eggs 80 o p08 f I 39 Sperm I 39 20 702 W Genotype frequencies p2064 RR 2pq032 Rr q2004 rr Allele frequencies p08 R q02 r Allele Frequencies At a later date you determine the genotypes of 500 individuals and find the following 280 RR 165 Rr 55 rr Frequency of R aka quotpquot 280 280 165 725 R alleles in the pop 725 1000 0725 Frequency of r aka quotqquot 165 55 55 275 r alleles in the pop 2751000 0275 Allele Frequencies The frequencies of alleles R and r have changed 320 RR 280 RR T1 160 Rr T2 165 Rr 20 rr 55 rr p08 q02 pO725 q0275 The population has EVO LV E D Ha rdyWein berg Eq uation For a two allele locus Let p the frequency of one allele in the population usually the dominant Let q the frequency of the other allele No cethat pq1 p1 q q1 p Genotypes should occur in the population according to Ha rdyWein berg Eq uation p2 proportion of population that is homozygous for the first allele eg RR qu proportion of population that is heterozygous eg Rr q2 proportion of population that is homozygous for the second allele eg rr Ha rdyWein berg Eq uation Given either p or q one can solve for the rest of the above equa on What wouldqbe ifp 06 What wouleque ifp 05 Ha rdyWein berg Eq uation Given the frequency of either homozygous genotype the rest of the equation can be solved What wouldqbe ipr 049 Hintqq2
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