ELEMENTS OF BIOL CHEM
ELEMENTS OF BIOL CHEM BICH 303
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This 6 page Class Notes was uploaded by Sylvester Mante on Wednesday October 21, 2015. The Class Notes belongs to BICH 303 at Texas A&M University taught by Timothy Devarenne in Fall. Since its upload, it has received 27 views. For similar materials see /class/225849/bich-303-texas-a-m-university in Biochemistry at Texas A&M University.
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Date Created: 10/21/15
Amino acids The building blocks of proteins Linked together by peptide bond amide to form protein Order sequence of amino acids critical to protein function same amp makeup of aa but not same protein lt gt C O IndIVIdualaa O O39o Amino acids General structure ofan amino acid amino group ozamino group a gw c 1 C carboxyl group a C b H R chain side chain Rgroup determines the 31 onquot ca identity of the aa H 11 VOO hydrogen Amino Carboxyl all are bound to group group occarbon Amino acid structure stereochemistry 3 D structure is tetrahedral Amino acids are tetrahedral structures Amino acids Amino acids are chiral refers to having nonsuperimposable mirror images acarbon is a chiral center having 4 different groups attached to occarbon Stereoisomers Am two possible aa forms based on mirror image tetrahedral two forms are not superimposable gives a handedness to aa such as left and right hand 1 Amino acids 2 forms of amino acids L and D amino acid stereoisomers based on the stereochemistry of glyceraldehyde L left handed D right handed based on amino group position around occarbon chiral center only L amino acids found in proteins aka ocamino acids D amino acids not found in proteins found in bacterial cell walls glycine is only aa with out chirality but does have L and D forms a cHo cHo HOgt ltH Hgt ltOH IZHOOH IHQOH cH2OH H3NC H L Glyceraldehyde D Clyc eraldehyde I H glycine QOOH COOH R group E H3Ngt ltH H gltNH3 H3 6H3 L Alauine D Alauine a a want Thamsn Nonpolar or hydrophobic Amino acids based on R group side chain a up u u u 5 39 5 1L 39 a W amp 1 Weix m m m mm mm Mmu Polar unchar ed m J WNW km M x mm mm Galamy c 5 micquot J l g 2 mumm m m mv wasgt137 2m 1 uwrunrn J mm m m 2 a 5 mm m u ems Brnaksrm e mmn s 2006 Ermksmnle mnnsnn