MOLEC GENETICS II
MOLEC GENETICS II MCDB 101B
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This 3 page Class Notes was uploaded by Erika Kuvalis on Thursday October 22, 2015. The Class Notes belongs to MCDB 101B at University of California Santa Barbara taught by Christofferse in Fall. Since its upload, it has received 56 views. For similar materials see /class/226900/mcdb-101b-university-of-california-santa-barbara in Molecular, Cellular And Developmental Biology at University of California Santa Barbara.
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Date Created: 10/22/15
MCDB 1018 3292010 95900 PM What is a gene o DNA sequences defined by all cisacting mutations that disrupt the normal function of a single gene o Genes are sequences of DNA that often encode proteins 0 Only about 1 of the human genome codes for proteins The rest are noncoding regions DNA resides within cells packaged as units called chromosomes o The entire collection of chromosomes in each cell of an organism is called a genome o Humans have 23 pairs of chromosomes o The human genome has about 3 x 10A9 base pairs and estimated 30000 40000 genes Proteins interact with DNA and other proteins o Biological systems function as complex interactive networks of proteins and DNA that interact with one another Many genes have similar functions in very different organisms o Conservation across many different levels Genetic techniques permit the dissection of complexity o Genes can be identified and inactivated one at a time using genetic techniques o Dissection of genomes genebygene unravels the complexity of biological systems o The challenge for modern biology lies in understanding how the multitude of networks of genes and higher level systems interact to produce complex systems Genome sequencing projects are a step in understanding the complexity of genomes Predictive and Preventative Medicine reasons to study genetics o Discovery of genes with variations that cause or predispose one to disease will continue at a rapid pace O O O 0 Gene therapy Diagnostics Therapeutic drugs to block or reverse effects of mutant genes Detection of disease and treatment before onset may increase life span significantly 3292010 95900 PM
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