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This 2 page Class Notes was uploaded by Jess Graff on Friday March 25, 2016. The Class Notes belongs to BMS 508 at University of New Hampshire taught by Mary Katherine Lockwood, PhD in Spring 2016. Since its upload, it has received 25 views. For similar materials see Human Anatomy and Physiology II in Biological Sciences at University of New Hampshire.
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Date Created: 03/25/16
BMS 508.03 3/21/2016 Chapter 22 (cont) Lymph and Immunity (cont) Immune System Development • 4 Categories of Allergic Reactions • Immediate hypersensitivity (Type I) • Cytotoxic reactions (Type II) • Immune complex disorders (Type III) • Delayed hypersensitivity (Type IV) • Type I Allergy • Also called immediate hypersensitivity • A rapid and severe response to the presence of an antigen • Most commonly recognized type of allergy • Includes allergic rhinitis (environmental allergies) • Sensitization leads to: • Production of large quantities of IgE antibodies distributed throughout the body • Second exposure leads to: • Massive inflammation of affected tissues • Severity of reaction depends on: • Individual sensitivity • Locations involved • Allergens (antigens that trigger reaction) in bloodstream may cause anaphylaxis • Anaphylaxis • Can be fatal • Affects cells throughout body • Changes capillary permeability • Produces swelling (hives) on skin • Smooth muscles of respiratory system contract • Make breathing difficult • Peripheral vasodilation • Can cause circulatory collapse (anaphylactic shock) • Antihistamines • Drugs that block histamine released by mast cells • Can relieve mild symptoms of immediate hypersensitivity • Benadryl • Stress and the Immune Response • Glucocorticoids • Secreted to limit immune response • Long-term secretion (chronic stress) • Inhibits immune response • Lowers resistance to disease • Functions of Glucocorticoids • Depression of the inflammatory response • Reduction in abundance and activity of phagocytes • Inhibition of interleukin secretion
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